文献检索，用中文搜 PubMed

Suppr 超能文献

核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

J Physiol. 1974 Jun;239(2):237-49. doi: 10.1113/jphysiol.1974.sp010566.

A double sucrose gap technique has been combined with an optical method of measuring the movement of the preparation and applied to rat ventricular trabeculae.2. Experiments performed in normal McEwen and in depleted sodium solutions with and without tetrodotoxin, manganese or predepolarization suggest that the fast inward current is not as important as the slow inward current in determining the contractile strength. Furthermore, there is a marked similarity between potential dependence of the slow inward current and the contraction, particularly in sodium-depleted fluids.3. The appearance of a staircase response associated with a series of depolarizations, in normal McEwen, may mean that there is an intervention of a further, possibly intracellular, stage between inward current and contraction, as suggested by earlier experiments on frog as well as on mammalian heart.

双蔗糖间隙技术已与一种测量标本运动的光学方法相结合，并应用于大鼠心室小梁。
在正常的麦克尤恩溶液以及含有和不含有河豚毒素、锰或预去极化的低钠溶液中进行的实验表明，在决定收缩强度方面，快速内向电流不如缓慢内向电流重要。此外，缓慢内向电流的电位依赖性与收缩之间存在明显的相似性，特别是在低钠溶液中。
在正常的麦克尤恩溶液中，与一系列去极化相关的阶梯反应的出现，可能意味着如早期对青蛙和哺乳动物心脏的实验所表明的那样，在内向电流和收缩之间存在另一个可能是细胞内的阶段的干预。

J Physiol. 1974 Jun;239(2):237-49. doi: 10.1113/jphysiol.1974.sp010566.

A double sucrose gap technique has been combined with an optical method of measuring the movement of the preparation and applied to rat ventricular trabeculae.2. Experiments performed in normal McEwen and in depleted sodium solutions with and without tetrodotoxin, manganese or predepolarization suggest that the fast inward current is not as important as the slow inward current in determining the contractile strength. Furthermore, there is a marked similarity between potential dependence of the slow inward current and the contraction, particularly in sodium-depleted fluids.3. The appearance of a staircase response associated with a series of depolarizations, in normal McEwen, may mean that there is an intervention of a further, possibly intracellular, stage between inward current and contraction, as suggested by earlier experiments on frog as well as on mammalian heart.

双蔗糖间隙技术已与一种测量标本运动的光学方法相结合，并应用于大鼠心室小梁。
在正常的麦克尤恩溶液以及含有和不含有河豚毒素、锰或预去极化的低钠溶液中进行的实验表明，在决定收缩强度方面，快速内向电流不如缓慢内向电流重要。此外，缓慢内向电流的电位依赖性与收缩之间存在明显的相似性，特别是在低钠溶液中。
在正常的麦克尤恩溶液中，与一系列去极化相关的阶梯反应的出现，可能意味着如早期对青蛙和哺乳动物心脏的实验所表明的那样，在内向电流和收缩之间存在另一个可能是细胞内的阶段的干预。