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[双副肿瘤综合征与肺间变性癌。肿瘤组织中的抗利尿激素和促肾上腺皮质激素水平(作者译)]

[Double paraneoplastic syndrome and anaplastic carcinoma of the lung. ADH and ACTH levels in the tumoral tissue (author's transl)].

作者信息

Dournon E, Fichet D, Trinh D H, Decroix G, Le Quintrec Y

出版信息

Ann Med Interne (Paris). 1979 Dec;130(12):635-9.

PMID:44161
Abstract

A double paraneoplasic syndrome with hypersecretion of ADH and ACTH revealed the presence of a small cell bronchial cancer in a man aged 62 years. Water and electrolyte anomalies due to the hypersecretions were of such a degree that an occlusive syndrome occurred. Very high levels of ADH and ACTH were found in the tumoral tissue. The measurement of these levels is rarely conducted at the present time but was able to define the mechanism of abnormal secretion of these two hormones in this case.

摘要

一名62岁男性出现抗利尿激素(ADH)和促肾上腺皮质激素(ACTH)分泌过多的双重副肿瘤综合征,提示存在小细胞支气管癌。由于激素分泌过多导致的水和电解质异常程度严重,引发了闭塞综合征。在肿瘤组织中发现了极高水平的ADH和ACTH。目前很少进行这些激素水平的检测,但在该病例中能够明确这两种激素异常分泌的机制。

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