Bernat M, Renier J C, Rebel A, Jallet P
Rev Rhum Mal Osteoartic. 1979 Jan;46(1):7-18.
The authors report on the clinical, biological and radiological anomalies observed in a series of 42 cases of idiopathic hypercalciuria. An histological bone study showed "osteomalacia" type changes (an increase in the osteoid volume and a decrease in the mineralization speed). The Ca45 isotope studies showed that there was an exchangable pool of calcium and a turnover, which was generally low. A study of the kidney functions revealed a decrease in the tubular reabsorption of calcium, while that of phosphorous remained within normal limits. There was no case of hyperparathyroidism in this series. The authors pose the question of whether the failure of calcium to settle on the tissues and the lack of tubular reabsorption of calcium, does not result from the relatively ineffective action of the endogenous circulating parathyroid hormone.
作者报告了在42例特发性高钙尿症患者中观察到的临床、生物学和放射学异常情况。一项组织学骨研究显示出“骨软化症”类型的变化（类骨质体积增加，矿化速度降低）。Ca45同位素研究表明存在一个可交换的钙池和钙周转，其通常较低。一项肾功能研究显示钙的肾小管重吸收减少，而磷的肾小管重吸收仍在正常范围内。该系列中无甲状旁腺功能亢进病例。作者提出了一个问题，即钙在组织上沉积失败以及钙的肾小管重吸收缺乏，是否并非由内源性循环甲状旁腺激素相对无效的作用所致。
