Knoblauch A, Baumann R, Frey-Wettstein M, Siebenmann R, Kistler H J
Schweiz Med Wochenschr. 1979 Feb 3;109(5):158-63.
Bone marrow necrosis was observed in a 23-year-old pregnant woman with severe anemia and thrombocytopenia due to bilateral ovarian carcinoma. After removal of the primary tumors, the hematological findings returned to normal, but the progression of the metastasis lead to respiratory insufficiency and death. The possible mechanisms leading to bone marrow necrosis are discussed. In our case, it could be shown that emboli of tumor cells into the vessels of the bone marrow lead to the necrosis of the marrow. The embolization was temporarily stopped after removal of the ovaries.
在一名23岁因双侧卵巢癌导致严重贫血和血小板减少的孕妇中观察到骨髓坏死。切除原发性肿瘤后，血液学检查结果恢复正常，但转移的进展导致呼吸功能不全并死亡。本文讨论了导致骨髓坏死的可能机制。在我们的病例中，可以证明肿瘤细胞栓子进入骨髓血管导致骨髓坏死。切除卵巢后，栓塞暂时停止。
