非霍奇金淋巴瘤的胸内表现
Intrathoracic manifestations in non-Hodgkin's lymphoma.
作者信息
Manoharan A, Pitney W R, Schonell M E, Bader L V
出版信息
Thorax. 1979 Feb;34(1):29-32. doi: 10.1136/thx.34.1.29.
A total of 16 of 86 patients (19%) with non-Hodgkin's lymphoma were found to have intrathoracic disease in this retrospective study. Paratracheal, mediastinal, and hilar lymphadenopathy was the commonest manifestation followed by pulmonary lesions and pleural effusion. The lymphoma was at an advanced clinical stage in all the patients with intrathoracic disease. About one-third of the intrathoracic lesions first developed at the time of relapse after successful initial therapy. There was a better response to therapy when intrathoracic disease was part of the initial presentation than when it was a manifestation of relapse. If it did not respond to therapy it was always indicative of a poor prognosis.
在这项回顾性研究中，86例非霍奇金淋巴瘤患者中有16例（19%）被发现存在胸内病变。气管旁、纵隔和肺门淋巴结肿大是最常见的表现，其次是肺部病变和胸腔积液。所有有胸内病变的患者淋巴瘤均处于临床晚期。约三分之一的胸内病变在初始治疗成功后的复发时首次出现。与胸内病变是复发表现时相比，当胸内病变是初始表现的一部分时，对治疗的反应更好。如果对治疗无反应，这始终提示预后不良。
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