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Factors affecting the metabolism of phenacetin. I. Influence of dose, chronic dosage, route of administration and species on the metabolism of (1-14C-acetyl)phenacetin.

作者信息

Smith R L, Timbrell J A

出版信息

Xenobiotica. 1974 Aug;4(8):489-501. doi: 10.3109/00498257409052101.

DOI:10.3109/00498257409052101
PMID:4423172
Abstract
摘要

相似文献

1
Factors affecting the metabolism of phenacetin. I. Influence of dose, chronic dosage, route of administration and species on the metabolism of (1-14C-acetyl)phenacetin.影响非那西丁代谢的因素。I. 剂量、长期给药、给药途径及物种对（1-¹⁴C-乙酰基）非那西丁代谢的影响。
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引用本文的文献

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Analgesic nephropathy: a reassessment of the role of phenacetin and other analgesics.镇痛剂肾病：对非那西丁及其他镇痛剂作用的重新评估
Drugs. 1982 Jan-Feb;23(1-2):75-149. doi: 10.2165/00003495-198223010-00004.
2
Kinetics and metabolism of paracetamol and phenacetin.对乙酰氨基酚和非那西丁的动力学与代谢
Br J Clin Pharmacol. 1980 Oct;10 Suppl 2(Suppl 2):291S-298S. doi: 10.1111/j.1365-2125.1980.tb01812.x.
3
Animal experiments regarding a possible carcinogenic effect of phenacetin on the resting and proliferating urothelium stimulated by cyclophosphamide.
关于非那西丁对环磷酰胺刺激下的静止和增殖尿路上皮可能致癌作用的动物实验。
J Cancer Res Clin Oncol. 1983;105(1):38-47. doi: 10.1007/BF00391830.
4
Generation of reactive species and fate of thiols during peroxidase-catalyzed metabolic activation of aromatic amines and phenols.芳香胺和酚类在过氧化物酶催化的代谢活化过程中活性物质的产生及硫醇的命运
Environ Health Perspect. 1985 Dec;64:253-7. doi: 10.1289/ehp.8564253.
5
Metabolism of paracetamol and phenacetin in relation to debrisoquine oxidation phenotype.对乙酰氨基酚和非那西丁的代谢与异喹胍氧化表型的关系。
Eur J Clin Pharmacol. 1991;40(6):547-52. doi: 10.1007/BF00279967.
6
Metabolism of phenacetin and N-hydroxyphenacetin in isolated rat hepatocytes.
Naunyn Schmiedebergs Arch Pharmacol. 1978 Nov;305(2):173-80. doi: 10.1007/BF00508289.