Belov V A, Vasil'ev V I, Gerasimov G M, Vishnevskaia I G
Vestn Khir Im I I Grek. 1979 Feb;122(2):95-8.
The renin activity and gluco- and mineralocorticoid adrenalocortical function were studied in 22 patients operated mainly on abdominal organs under the conditions of ketamine anesthesia. As noted, the ketamine injection followed with hypertension and tachicardia does not give rise to the renin activity and to the 11-OKS and aldosterone blood levels, as well. An evident trend to the increase of the concentration of the adrenocortical hormones, together with the occurrence of hypokemia and progressive hyperglycemia have been traced throughout the anesthesia and operation.
对22例主要接受腹部器官手术的患者在氯胺酮麻醉条件下的肾素活性以及糖皮质激素和盐皮质激素的肾上腺皮质功能进行了研究。如前所述，注射氯胺酮后出现的高血压和心动过速并未引起肾素活性以及血中11-氧皮质类固醇和醛固酮水平的升高。在整个麻醉和手术过程中，已发现肾上腺皮质激素浓度有明显升高趋势，同时伴有低钾血症和进行性高血糖症的出现。
