基因型依赖性对吗啡和海洛因的敏感性与耐受性：小鼠中阿片类药物诱导的奔跑行为与镇痛作用的分离 - Suppr

Suppr

超能文献

Genotype-dependent sensitivity and tolerance to morphine and heroin: dissociation between opiate-induced running and analgesia in the mouse.

作者信息

Oliverio A, Castellano C

出版信息

Psychopharmacologia. 1974;39(1):13-22. doi: 10.1007/BF00421454.

DOI:10.1007/BF00421454

PMID:4424979

Abstract

摘要

相似文献

Genotype-dependent sensitivity and tolerance to morphine and heroin: dissociation between opiate-induced running and analgesia in the mouse.基因型依赖性对吗啡和海洛因的敏感性与耐受性：小鼠中阿片类药物诱导的奔跑行为与镇痛作用的分离

Psychopharmacologia. 1974;39(1):13-22. doi: 10.1007/BF00421454.

Motivational effects of opiates in conditioned place preference and aversion paradigm--a study in three inbred strains of mice.阿片类药物在条件性位置偏爱和厌恶范式中的动机效应——三种近交系小鼠的研究。

Psychopharmacology (Berl). 2009 Dec;207(2):245-55. doi: 10.1007/s00213-009-1672-7. Epub 2009 Sep 29.

Genetic dissociation of multiple morphine effects among C57BL/6J, DBA/2J and C3H/HeJ inbred mouse strains.C57BL/6J、DBA/2J和C3H/HeJ近交系小鼠品系中多种吗啡效应的遗传分离。

Physiol Behav. 1989 Jul;46(1):69-74. doi: 10.1016/0031-9384(89)90324-7.

Morphine sensitivity and tolerance: a genetic investigation in the mouse.吗啡敏感性与耐受性：小鼠的一项遗传学研究

Psychopharmacologia. 1975 Jun 19;42(3):219-24. doi: 10.1007/BF00421259.

Comparison of the effects of morphine on locomotor activity, analgesia and primary and protracted physical dependence in six mouse strains.吗啡对六种小鼠品系的运动活性、镇痛作用以及初次和持续性身体依赖性影响的比较。

J Pharmacol Exp Ther. 1977 May;201(2):368-74.

Morphine-induced running analgesia in two strains of mice following septal lesions or modification of brain amines.隔区损伤或脑胺改变后两种品系小鼠中吗啡诱导的跑步镇痛作用。

Naunyn Schmiedebergs Arch Pharmacol. 1975;288(4):355-70. doi: 10.1007/BF00501282.

Strain-dependent effects of morphine injected into the periaqueductal gray area of mice.注射到小鼠中脑导水管周围灰质区域的吗啡的应变依赖性效应。

Braz J Med Biol Res. 1991;24(3):291-9.

Differential genetic mediation of sensitivity to morphine in genetic models of opiate antinociception: influence of nociceptive assay.阿片类镇痛遗传模型中吗啡敏感性的差异基因介导：伤害性检测的影响

J Pharmacol Exp Ther. 1996 Feb;276(2):532-44.

A genetic analysis of the response to morphine in mice: analgesia and running.小鼠对吗啡反应的遗传分析：镇痛与奔跑

Psychopharmacologia. 1975 Jun 19;42(3):249-54. doi: 10.1007/BF00421264.

A genetic analysis of morphine-induced running and analgesia in the mouse.小鼠中吗啡诱导的跑步行为和镇痛作用的遗传分析。

Psychopharmacologia. 1975;41(3):197-200. doi: 10.1007/BF00428924.

引用本文的文献

The influence of morphine treatment on the opioid propeptide gene expression in the forebrain of two inbred mouse strains with different sensitivity to opioids.吗啡处理对两种对阿片类药物敏感性不同的近交系小鼠前脑阿片前体肽基因表达的影响。

Pharmacol Rep. 2025 Aug 14. doi: 10.1007/s43440-025-00769-8.

Physiological dependence to mitragynine indicated by a rapid cross-dependence procedure with heroin-dependent mice.通过与海洛因依赖小鼠的快速交叉依赖程序表明对帽柱木碱的生理依赖。

Psychopharmacology (Berl). 2022 Mar;239(3):897-908. doi: 10.1007/s00213-022-06080-1. Epub 2022 Feb 2.

Retrospectively assessed subjective effects of initial opioid use differ between opioid misusers with opioid use disorder (OUD) and those who never progressed to OUD: Data from a pilot and a replication sample.回顾性评估有阿片类药物使用障碍（OUD）和从未进展为 OUD 的阿片类药物滥用者初始阿片类药物使用的主观效应不同：来自一个试点和一个复制样本的数据。

J Neurosci Res. 2022 Jan;100(1):353-361. doi: 10.1002/jnr.24643. Epub 2020 May 28.

The Behavioral Effects of the Antidepressant Tianeptine Require the Mu-Opioid Receptor.抗抑郁药噻奈普汀的行为效应需要μ-阿片受体。

Neuropsychopharmacology. 2017 Sep;42(10):2052-2063. doi: 10.1038/npp.2017.60. Epub 2017 Mar 17.

Potentiation of brain stimulation reward by morphine: effects of neurokinin-1 receptor antagonism.吗啡增强脑刺激奖励：神经激肽-1 受体拮抗作用。

Psychopharmacology (Berl). 2012 Mar;220(1):215-24. doi: 10.1007/s00213-011-2469-z. Epub 2011 Sep 10.

Identification of candidate genes and gene networks specifically associated with analgesic tolerance to morphine.鉴定与吗啡镇痛耐受性特异性相关的候选基因和基因网络。

J Neurosci. 2009 Apr 22;29(16):5295-307. doi: 10.1523/JNEUROSCI.4020-08.2009.

Heroin-induced locomotor activity and conditioned place preference in C57BL/6J and 129P3/J mice.海洛因诱导的C57BL/6J和129P3/J小鼠的自发活动及条件性位置偏爱

Neurosci Lett. 2008 Aug 8;440(3):284-8. doi: 10.1016/j.neulet.2008.05.103. Epub 2008 Jun 4.

Atypical anxiolytic-like response to naloxone in benzodiazepine-resistant 129S2/SvHsd mice: role of opioid receptor subtypes.苯二氮䓬类耐药的129S2/SvHsd小鼠对纳洛酮的非典型抗焦虑样反应：阿片受体亚型的作用

Psychopharmacology (Berl). 2006 Aug;187(3):345-55. doi: 10.1007/s00213-006-0435-y. Epub 2006 Jun 27.

Gene expression profiling in the striatum of inbred mouse strains with distinct opioid-related phenotypes.具有不同阿片类药物相关表型的近交系小鼠纹状体中的基因表达谱分析。

BMC Genomics. 2006 Jun 13;7:146. doi: 10.1186/1471-2164-7-146.

HS014, a selective melanocortin-4 (MC4) receptor antagonist, modulates the behavioral effects of morphine in mice.HS014是一种选择性黑皮质素-4（MC4）受体拮抗剂，可调节吗啡对小鼠的行为影响。

Psychopharmacology (Berl). 2005 Jul;180(2):279-85. doi: 10.1007/s00213-005-2166-x. Epub 2005 Feb 18.

本文引用的文献

The effect of cortisone, desoxycorticosterone, and adrenocorticotrophic hormone upon the responses of animals to analgesic drugs.可的松、脱氧皮质酮及促肾上腺皮质激素对动物对镇痛药反应的影响。

J Pharmacol Exp Ther. 1951 Sep;103(1):93-105.

A simple method for producing tolerance to dihydromorphinone in mice.一种使小鼠对二氢吗啡酮产生耐受性的简单方法。

J Pharmacol Exp Ther. 1963 May;140:149-54.

Drug-induced changes in brain acetylcholine.药物引起的大脑乙酰胆碱变化。

Br J Pharmacol Chemother. 1962 Oct;19(2):226-34. doi: 10.1111/j.1476-5381.1962.tb01184.x.

Synthetic analgesics. II. Dithienylbutenyl- and dithienylbutylamines.合成镇痛药。II. 二噻吩基丁烯基胺和二噻吩基丁胺。

J Pharmacol Exp Ther. 1953 Mar;107(3):385-93.

Addiction liability of albino rats: breeding for quantitive differences in morphine drinking.白化大鼠的成瘾易感性：针对吗啡饮用量的定量差异进行选育。

Science. 1967 Aug 4;157(3788):561-3. doi: 10.1126/science.157.3788.561.

Tolerance to opioid narcotics. I. Tolerance to the "running fit" caused by levorphanol in the mouse.对阿片类麻醉药的耐受性。I. 小鼠对左啡诺引起的“奔跑发作”的耐受性。

J Pharmacol Exp Ther. 1969 Oct;169(2):175-84.

Effects of narcotic analgesics upon the locomotor activity and brain catecholamine content of the mouse.麻醉性镇痛药对小鼠运动活性及脑内儿茶酚胺含量的影响。

J Pharmacol Exp Ther. 1971 Feb;176(2):472-9.

Effect of reserpine, alpha-methyl-p-tyrosine, p-chlorophenylalanine and pargyline on levorphanol-induced running activity in mice.利血平、α-甲基对酪氨酸、对氯苯丙氨酸和帕吉林对小鼠左啡诺诱导的奔跑活动的影响。

Arch Int Pharmacodyn Ther. 1969 Jun;179(2):419-24.

Genetic analysis of susceptibility to morphine addiction in inbred mice.近交系小鼠对吗啡成瘾易感性的遗传分析。

Ann Med Exp Biol Fenn. 1971;49(2):73-8.

Genetic analysis of avoidance, maze, and wheel-running behaviors in the mouse.小鼠回避、迷宫及转轮行为的遗传分析。

J Comp Physiol Psychol. 1972 Jun;79(3):459-73. doi: 10.1037/h0032835.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验