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[慢性胰腺炎患者尿液中的酮糖]

[Keto sugars in the urine of patients with chronic pancreatitis].

作者信息

Gorodetskiĭ V K, Isakova Z S

出版信息

Vopr Med Khim. 1979 Mar-Apr;25(2):153-7.

PMID:442586
Abstract

Simultaneously with fructose and sucrose, five oligosaccharides, containing fructose residue and exhibiting reducing properties, were found in urine of patients with chronic pancreatitis and with liver impairments caused by ethanol intoxication. Four of the oligosaccharides were trisaccharides, containing fructose residue and two residues of glucose as well as one tetrassaccharide, comprizing a residue of fructose and three residues of glucose. The fructose residue occupied the terminal position in all the oligosaccharides. The oligosaccharides found in urine of the patients were dissimilar in the types of link between residues of glucose and between residues of fructose and glucose; these oligosaccharides exhibited different chromatographic mobility.

摘要

在慢性胰腺炎患者以及乙醇中毒所致肝损伤患者的尿液中,发现与果糖和蔗糖同时存在的五种含有果糖残基且具有还原性的低聚糖。其中四种低聚糖为三糖,含有果糖残基和两个葡萄糖残基,还有一种四糖,由一个果糖残基和三个葡萄糖残基组成。果糖残基在所有低聚糖中均占据末端位置。患者尿液中发现的这些低聚糖在葡萄糖残基之间以及果糖与葡萄糖残基之间的连接类型上有所不同;这些低聚糖表现出不同的色谱迁移率。

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