Tsagikian T A, Nesterova A P, Frolova I A
Vopr Med Khim. 1979 Mar-Apr;25(2):161-6.
Activities of main pancreatic enzymes as well as activity of trypsin inhibitor were studied in blood serum, duodenal contents and urine in course of investigations of the exocrinic function of pancreas in patients. The exocrinic function of pancreas was found to be impaired in chronic enterocolitis. The impairment of the gland secretion, caused by inflammatory and atrophic alterations in intestine, might be one of the factors responsible for alterations in the enzymatic activity and in activity of trypsin inhibitor. Complex examination of the pancreatic enzymes and of trypsin inhibitor supplied an adequate information on the state of exocrinic function of pancreatic gland in the patients with chronic enterocolitis.
在对患者胰腺外分泌功能的研究过程中，对血清、十二指肠内容物和尿液中的主要胰腺酶活性以及胰蛋白酶抑制剂活性进行了研究。发现慢性小肠结肠炎患者的胰腺外分泌功能受损。肠道炎症和萎缩性改变引起的腺体分泌受损，可能是导致酶活性和胰蛋白酶抑制剂活性改变的因素之一。对胰腺酶和胰蛋白酶抑制剂的综合检查为慢性小肠结肠炎患者胰腺外分泌功能的状态提供了充分信息。
