• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Altered ribonucleotide reductase activity in mammalian tissue culture cells resistant to hydroxyurea.

作者信息

Lewis W H, Wright J A

出版信息

Biochem Biophys Res Commun. 1974 Oct 8;60(3):926-33. doi: 10.1016/0006-291x(74)90403-3.

DOI:10.1016/0006-291x(74)90403-3
PMID:4429567
Abstract
摘要

相似文献

1
Altered ribonucleotide reductase activity in mammalian tissue culture cells resistant to hydroxyurea.对羟基脲耐药的哺乳动物组织培养细胞中核糖核苷酸还原酶活性的改变。
Biochem Biophys Res Commun. 1974 Oct 8;60(3):926-33. doi: 10.1016/0006-291x(74)90403-3.
2
Correlation between levels of ferritin and the iron-containing component of ribonucleotide reductase in hydroxyurea-sensitive, -resistant, and -revertant cell lines.羟基脲敏感、耐药和回复细胞系中，铁蛋白水平与核糖核苷酸还原酶含铁成分之间的相关性。
Biochem Cell Biol. 1991 Sep;69(9):635-42. doi: 10.1139/o91-094.
3
A series of N-carbamoyloxyurea resistant cell lines with alterations in ribonucleotide reductase: lack of coordination in pyrimidine and purine reductase activity.
Can J Biochem Cell Biol. 1983 Feb-Mar;61(2-3):120-9. doi: 10.1139/o83-018.
4
Ribonucleotide reductase from wild type and hydroxyurea-resistant chinese hamster ovary cells.来自野生型和羟基脲抗性中国仓鼠卵巢细胞的核糖核苷酸还原酶。
J Cell Physiol. 1978 Oct;97(1):87-97. doi: 10.1002/jcp.1040970109.
5
Altered expression of ribonucleotide reductase and role of M2 gene amplification in hydroxyurea-resistant hamster, mouse, rat, and human cell lines.核糖核苷酸还原酶表达的改变以及M2基因扩增在羟基脲抗性仓鼠、小鼠、大鼠和人类细胞系中的作用。
Somat Cell Mol Genet. 1987 Mar;13(2):155-65. doi: 10.1007/BF01534695.
6
Studies of mammalian ribonucleotide reductase activity in intact permeabilized cells: a genetic approach.
Adv Enzyme Regul. 1980;19:105-27. doi: 10.1016/0065-2571(81)90011-x.
7
Altered ribonucleotide reductase activity in drug-resistant mammalian cells detected by an assay procedure for intact cells.
Enzyme. 1980;25(4):220-7. doi: 10.1159/000459256.
8
Alterations in the components of ribonucleotide reductase in hydroxyurea-resistant hamster cells.
Biosci Rep. 1983 Aug;3(8):741-8. doi: 10.1007/BF01120985.
9
Characterization of a mouse cell line selected for hydroxyurea resistance by a stepwise procedure: drug-dependent overproduction of ribonucleotide reductase activity.通过逐步程序选择的对羟基脲具有抗性的小鼠细胞系的特性：核糖核苷酸还原酶活性的药物依赖性过量产生。
Somat Cell Mol Genet. 1986 Mar;12(2):121-31. doi: 10.1007/BF01560659.
10
Isolation of hydroxyurea-resistant CHO cells with altered levels of ribonucleotide reductase.
Somatic Cell Genet. 1979 Jan;5(1):83-96. doi: 10.1007/BF01538788.

引用本文的文献

1
Sickle Cell Disease in Sub-Saharan Africa.撒哈拉以南非洲地区的镰状细胞病
Hematol Oncol Clin North Am. 2016 Apr;30(2):343-58. doi: 10.1016/j.hoc.2015.11.005. Epub 2016 Jan 28.
2
Increased Rrm2 gene dosage reduces fragile site breakage and prolongs survival of ATR mutant mice.Rrm2基因剂量增加可减少脆性位点断裂并延长ATR突变小鼠的生存期。
Genes Dev. 2015 Apr 1;29(7):690-5. doi: 10.1101/gad.256958.114.
3
Chromosome damage and repair in children with sickle cell anaemia and long-term hydroxycarbamide exposure.长期羟基脲暴露的镰状细胞贫血儿童的染色体损伤与修复。
Br J Haematol. 2011 Jul;154(1):134-40. doi: 10.1111/j.1365-2141.2011.08698.x. Epub 2011 May 4.
4
Effects of hydroxyurea on monoclonal antibody production induced by anti-mIgG and LPS stimulation on murine B cell hybridomas.羟基脲对抗 mIgG 和 LPS 刺激诱导的鼠 B 细胞杂交瘤单克隆抗体产生的影响。
Cytotechnology. 2010 Jul;62(3):205-15. doi: 10.1007/s10616-010-9278-9. Epub 2010 May 21.
5
The influence of high dose hydroxyurea on the incorporation of 5-iodo-2-deoxyuridine (IUdR) by human bone marrow and tumour cells in vivo.高剂量羟基脲对人骨髓和肿瘤细胞在体内摄取5-碘-2-脱氧尿苷（IUdR）的影响。
Br J Cancer. 1993 Apr;67(4):644-9. doi: 10.1038/bjc.1993.120.
6
Hydroxyurea-resistant mouse L cells with elevated levels of drug-resistant ribonucleotide reductase activity.
Biochem Genet. 1980 Apr;18(3-4):311-31. doi: 10.1007/BF00484244.
7
Ornithine decarboxylase induction in cells stimulated to proliferate differs from that in continuously dividing cells.在被刺激增殖的细胞中鸟氨酸脱羧酶的诱导与在持续分裂的细胞中的诱导不同。
Biochem J. 1980 May 15;188(2):375-80. doi: 10.1042/bj1880375.
8
Chromosome-mediated gene transfer of hydroxyurea resistance and amplification of ribonucleotide reductase activity.羟基脲抗性的染色体介导基因转移及核糖核苷酸还原酶活性的扩增
Mol Cell Biol. 1983 Jun;3(6):1053-61. doi: 10.1128/mcb.3.6.1053-1061.1983.
9
Overproduction of the free radical of ribonucleotide reductase in hydroxyurea-resistant mouse fibroblast 3T6 cells.羟基脲抗性小鼠成纤维细胞3T6中核糖核苷酸还原酶自由基的过度产生。
Proc Natl Acad Sci U S A. 1981 Apr;78(4):2159-63. doi: 10.1073/pnas.78.4.2159.
10
Chinese hamster ovary cell mutants resistant to DNA polymerase inhibitors. I. Isolation and biochemical genetic characterization.对DNA聚合酶抑制剂具有抗性的中国仓鼠卵巢细胞突变体。I. 分离与生化遗传特征分析。
Mol Gen Genet. 1985;200(3):393-400. doi: 10.1007/BF00425722.