Driscoll D J, Gillette P C, Hallman G L, Cooley D A, McNamara D G
Am J Cardiol. 1979 Jun;43(6):1175-80. doi: 10.1016/0002-9149(79)90150-4.
Because there is disagreement concerning the efficacy of and indication for permanent pacemaker implantation in children with postoperative complete (third degree) atrioventricular (A-V) block, experience in the management of this problem at one institution was reviewed. Thirty-four patients with postoperative complete atrioventricular block were identified. They ranged in age from 4 months to 22 years and in weight from 4 to 60 kg and were evaluated from 1 month to 20 years postoperatively. Complete A-V block developed within 24 hours of operation in 28 of the 34 patients. A permanent pacemaker was implanted in 13 of the 28. Death occurred in 4 of these 13 patients and in 5 of the remaining 15 patients who did not have an artificial permanent pacemaker. Complete A-V block developed later than 1 day (2 days to 4 months) postoperatively in 6 of the 34 patients; all 6 of these patients survived, and only 3 required permanent pacemaker implantation. Intracardiac electrophysiologic studies were performed by 14 of the 34 patients. The site of complete block was above the His bundle in 5, within the His bundle in 2, and below the His bundle in 4; it was undetermined in 3. The results of intracardiac electrophysiologic studies are important in delineating the natural history of surgically induced complete A-V block and in the clinical management of this lesion. Permanent pacemaker implantation is indicated if complete A-V block persists longer than 2 weeks postoperatively and if the site of the block is within or below the bundle of His.
由于对于永久性起搏器植入术在术后发生完全性(三度)房室传导阻滞儿童中的疗效和适应证存在分歧,我们回顾了一家机构处理该问题的经验。共确定了34例术后发生完全性房室传导阻滞的患者。他们的年龄从4个月至22岁,体重从4千克至60千克,术后评估时间为1个月至20年。34例患者中有28例在术后24小时内发生了完全性房室传导阻滞。这28例患者中有13例植入了永久性起搏器。这13例患者中有4例死亡,其余15例未植入永久性起搏器的患者中有5例死亡。34例患者中有6例在术后1天以后(2天至4个月)发生完全性房室传导阻滞;这6例患者均存活,其中只有3例需要植入永久性起搏器。34例患者中有14例进行了心内电生理研究。完全性传导阻滞部位在希氏束以上的有5例,在希氏束内的有2例,在希氏束以下的有4例;3例未确定。心内电生理研究结果对于描述手术诱发的完全性房室传导阻滞的自然病程以及该病变的临床处理具有重要意义。如果术后完全性房室传导阻滞持续超过2周,且阻滞部位在希氏束内或希氏束以下,则需要植入永久性起搏器。