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1976年日本风疹流行的眼部表现

Ocular manifestations of the 1976 rubella epidemic in Japan.

作者信息

Hara J, Fujimoto F, Ishibashi T, Seguchi T, Nishimura K

出版信息

Am J Ophthalmol. 1979 May;87(5):642-5. doi: 10.1016/0002-9394(79)90297-6.

Abstract

Of 79 cases of rubella during the 1976--1977 rubella epidemic in Japan, 56 (70.9%) had mild conjunctivitis. Six (7.6%) showed epithelial keratitis, but the epidemically estimated incidence of keratitis was about 2% (two cases with rubella keratitis per 75 cases of rubella). No evidence of disease of the anterior chamber or the fundus was observed. Characteristic features of keratitis in juvenile rubella were fine punctate epithelial opacities mainly disseminated in the central area of the cornea. The punctate lesions were about 0.1 mm in diameter on an average, but varied in number from a few to about 100. In many cases, keratitis developed about one week after skin rash and disappeared within one week with no sequelae.

摘要

在1976 - 1977年日本风疹流行期间的79例风疹病例中,56例(70.9%)有轻度结膜炎。6例(7.6%)表现为上皮性角膜炎,但据流行病估计角膜炎的发病率约为2%(每75例风疹中有2例风疹性角膜炎)。未观察到前房或眼底疾病的证据。青少年风疹性角膜炎的特征性表现为细小点状上皮混浊,主要散布在角膜中央区域。点状病变平均直径约为0.1毫米,但数量从几个到约100个不等。在许多病例中,角膜炎在皮疹出现约一周后发生,并在一周内消失,无后遗症。

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