Excretion of probenecid and its metabolites in bile and urine of rats.
作者信息
Conway W D, Melethil S
出版信息
J Pharm Sci. 1974 Oct;63(10):1551-4. doi: 10.1002/jps.2600631013.
PMID:4436787
Abstract
摘要
相似文献
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Excretion of probenecid and its metabolites in bile and urine of rats.丙磺舒及其代谢产物在大鼠胆汁和尿液中的排泄情况。
J Pharm Sci. 1974 Oct;63(10):1551-4. doi: 10.1002/jps.2600631013.
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Mass spectral identification of probenecid metabolites in rat bile.
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A gas chromatographic assay for probenecid and its metabolites in biological fluids.生物流体中丙磺舒及其代谢物的气相色谱测定法。
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Identification and renal excretion of probenecid metabolites in man.
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Biliary excretion of probenecid and its glucuronide.
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Effects of phenobarbital on biliary excretion of organic acids in male and female rats.苯巴比妥对雄性和雌性大鼠有机酸胆汁排泄的影响。
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Studies on the biliary excretion mechanisms of drugs. 3. Active transport of glucuronides into bile in rats.
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Probenecid disposition by parallel Michaelis-Menten and dose-dependent pseudo-first-order processes.丙磺舒通过平行的米氏过程和剂量依赖性伪一级过程进行处置。
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引用本文的文献
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Impact of Mrp2 on the biliary excretion and intestinal absorption of furosemide, probenecid, and methotrexate using Eisai hyperbilirubinemic rats.利用卫材高胆红素血症大鼠研究Mrp2对呋塞米、丙磺舒和甲氨蝶呤胆汁排泄及肠道吸收的影响。
Pharm Res. 2003 Jan;20(1):31-7. doi: 10.1023/a:1022238506509.
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Clinical pharmacokinetics of probenecid.丙磺舒的临床药代动力学。
Clin Pharmacokinet. 1981 Mar-Apr;6(2):135-51. doi: 10.2165/00003088-198106020-00004.
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Non-linear elimination and protein binding of probenecid.丙磺舒的非线性消除与蛋白结合
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