Welner A, Welner Z, Fishman R
Arch Gen Psychiatry. 1979 Jun;36(6):698-700. doi: 10.1001/archpsyc.1979.01780060088010.
Seventy-seven adolescent psychiatric inpatients, whose index hospitalization was at a mean age of 16, were followed up for eight to ten years after discharge. The important findings at follow-up were as follows. Twelve patients had bipolar affective disorder and were severely disabled (of these, 11 had a long-term clinical course and three committed suicide). Sixteen patients had unipolar depression: five had one depressive episode and were well throughout the follow-up period, one patient had many episodes with complete remissions, and the remaining ten patients had only partial remissions and their impairment of functioning corresponded to the severity of their symptoms. One of the ten committed suicide. Eighteen (23%) patients were psychiatrically well and functioned adequately throughout the follow-up period. Five had primary depressions, five had undiagnosed psychiatric illness, and eight were diagnosed as not having a psychiatric disorder.
77名青少年精神科住院患者,其首次住院时的平均年龄为16岁,出院后随访了8至10年。随访的重要发现如下。12名患者患有双相情感障碍且严重致残(其中11名病程较长,3名自杀)。16名患者患有单相抑郁症:5名有一次抑郁发作且在整个随访期间情况良好,1名患者有多次发作且完全缓解,其余10名患者仅部分缓解,其功能损害与症状严重程度相符。这10名患者中有1名自杀。18名(23%)患者在整个随访期间精神状况良好且功能正常。5名患有原发性抑郁症,5名患有未确诊的精神疾病,8名被诊断为没有精神障碍。