Jungstand W, Gutsche W, Wohlrabe K, Schulze W
Arch Geschwulstforsch. 1979;49(1):15-7.
Eight of fifteen Fluorenone-Azomethines without alkylating function have been found effective against the leukemia L 1210. Little modifications concerning the structure of the compounds caused loss of effectiveness. It seems remarkably that one corresponding derivative with a nitrogen mustard group (4) was ineffective. Correlations between chemical structure and biological effect have not yet been found.
15种无烷基化功能的芴酮-偶氮甲碱中有8种已被发现对白血病L 1210有效。化合物结构的微小改变会导致有效性丧失。值得注意的是，一种带有氮芥基团的相应衍生物（4）无效。尚未发现化学结构与生物效应之间的相关性。
