长期多次用绵羊红细胞免疫的家兔脾脏的组织学变化。
Histologic changes in the spleen of rabbits following long-term and multiple immunization with sheep red blood cells.
作者信息
Hałasa J, Dominiczak K, Podkowińska I, Braun J
出版信息
Arch Immunol Ther Exp (Warsz). 1979;27(1-2):29-36.
PMID:444042
Abstract
Results of immunologic and histologic studies on rabbits immunized with sheep red blood cells (SRBC) showed dependence of the immunologic response (PFC, RFC) on the histologic structure of the spleen, particularly width of the sinusoidal vessels. Histologic changes in the spleen are a result of immunization and their intensity is related to the dose of antigen. The influence of dosage of antigen and histologic structure of the spleen on regulation of the immunologic response are discussed.
摘要
对用绵羊红细胞（SRBC）免疫的兔子进行免疫和组织学研究的结果表明，免疫反应（PFC、RFC）依赖于脾脏的组织结构，特别是窦状血管的宽度。脾脏的组织学变化是免疫的结果，其强度与抗原剂量有关。本文讨论了抗原剂量和脾脏组织结构对免疫反应调节的影响。
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Histologic changes in the spleen of rabbits following long-term and multiple immunization with sheep red blood cells.长期多次用绵羊红细胞免疫的家兔脾脏的组织学变化。
Arch Immunol Ther Exp (Warsz). 1979;27(1-2):29-36.
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