Zolotarevskiĭ V B, Bukhteeva N F, Kogan E A
Arkh Patol. 1979;41(4):43-8.
Cytological examinations of punctates of 200 large mammary gland cysts distinguished three variants thereof: cysts without signs of epithelium proliferation; cysts with signs of epithelium proliferation; and cysts with signs of epithelium proliferation and atypia. In 12 operated patients with the cyst of the second variant no cancer was detected. Among 9 operated patients with cysts of the third variant 3 were found to have intraductal cancer with initial invasion (including one case of malignized cystadenopapilloma). Detection in cytological examinations of cysts with signs of epithelium proliferation and atypia is sufficient for excision biopsy. Such patients should be considered as a higher risk group.
对200个大型乳腺囊肿的穿刺物进行细胞学检查，区分出三种变体：无上皮增殖迹象的囊肿；有上皮增殖迹象的囊肿；有上皮增殖和异型性迹象的囊肿。在12例接受手术的第二种变体囊肿患者中，未检测到癌症。在9例接受手术的第三种变体囊肿患者中，有3例被发现患有伴有早期浸润的导管内癌（包括1例恶性化的囊性腺瘤性乳头状瘤）。在细胞学检查中检测到有上皮增殖和异型性迹象的囊肿，足以进行切除活检。这类患者应被视为高危人群。
