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[皮肤病中胶原纤维的异常形式]

[Unusual forms of collagen fibrils in dermatoses].

作者信息

Bragina E E, Karimberdyev D R

出版信息

Arkh Patol. 1979;41(4):54-8.

PMID:444089
Abstract

Electron microscopic examinations of the skin from foci of lesions in scleroderma, psoriasis, parapsoriasis, and lupus erythematosus revealed two types of unusual collagen structures consisting of loosely packed fibrils 5--8 nm in diameter with a cross-striation period of 150--170 and 80--90 nm. The former were localized in the epi- or perineurium of pulpless nervous fibers of the derma, the latter among collagen fibers. These structures appear to occur rather widely in collagen metabolism disorders (tumours of neurogenic origin, some skin tumours, collagen diseases).

摘要

对硬皮病、银屑病、副银屑病和红斑狼疮皮损部位皮肤进行的电子显微镜检查显示,存在两种异常的胶原结构,由直径5-8纳米的松散排列的纤维组成,横纹周期分别为150-170纳米和80-90纳米。前者位于无髓神经纤维的真皮表皮或神经束膜中,后者位于胶原纤维之间。这些结构似乎在胶原代谢紊乱(神经源性肿瘤、一些皮肤肿瘤、胶原病)中相当广泛地出现。

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