Purcell J J, Krachmer J H
Arch Ophthalmol. 1979 May;97(5):872-4. doi: 10.1001/archopht.1979.01020010430005.
A 4-year-old boy with severe, diffuse, asymptomatic, punctate, epithelial corneal erosions had bilateral sharply decreased corneal sensation with normal skin sensation in the distribution of the trigeminal nerves. Subsequent family studies disclosed five family members with similar corneal changes and decreased corneal sensation and no punctate erosions. None had decreased skin sensation in the distribution of the fifth cranial nerve. No environmental factors or evidence of local or systemic disease accounted for these findings.
一名4岁男孩患有严重、弥漫性、无症状的点状上皮性角膜糜烂,双侧角膜感觉明显减退,而三叉神经分布区域的皮肤感觉正常。随后的家族研究发现,有五名家族成员有类似的角膜变化和角膜感觉减退,但没有点状糜烂。他们中没有人在第五颅神经分布区域的皮肤感觉减退。没有环境因素或局部或全身疾病的证据可以解释这些发现。