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噪声-噪声对柯蒂氏器创伤后进行性坏死扩散的影响。

Noise-noise effect upon the spreading of the posttraumatic progressive necrosis in the organ of Corti.

作者信息

Voldrich L

出版信息

Arch Otorhinolaryngol. 1979;222(3):169-73. doi: 10.1007/BF00456312.

DOI:10.1007/BF00456312
PMID:444150
Abstract

Progressive necrosis of the organ of Corti caused by a disturbance of the ionic composition of the Cortilymph resulting from the infiltration of endolymph into the organi of Corti after traumatization of its barrier against the scala media, is greatly intensified by posttraumatic stimulation with noise of physiological intensities. This effect is attributed to oscillation of the cochlear partition, with resultant greater blending of the Cortilymph and the endolymph. Stimulation augments necrosis fourfold towards the base of the cochlea and twofold towards the helicotrema. Posttraumatic stimulation is one of the factors which markedly potentiate the regressive effect of acoustic trauma.

摘要

在耳蜗中,由于其与中阶之间的屏障受到创伤后,内淋巴渗入柯蒂氏器,导致柯蒂淋巴离子成分紊乱,进而引起柯蒂氏器进行性坏死。而创伤后受到生理强度噪声的刺激会极大地加剧这种坏死。这种效应归因于耳蜗隔板的振荡,导致柯蒂淋巴和内淋巴的混合加剧。刺激使朝向耳蜗底部的坏死增加四倍,朝向蜗孔的坏死增加两倍。创伤后刺激是显著增强声创伤退行性效应的因素之一。

相似文献

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Noise-noise effect upon the spreading of the posttraumatic progressive necrosis in the organ of Corti.噪声-噪声对柯蒂氏器创伤后进行性坏死扩散的影响。
Arch Otorhinolaryngol. 1979;222(3):169-73. doi: 10.1007/BF00456312.
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Reduction in noise-induced functional loss of the cochleae in mice with pre-existing cochlear dysfunction due to genetic interference of prestin.由于对prestin进行基因干扰,在已有耳蜗功能障碍的小鼠中,噪声诱导的耳蜗功能丧失减少。
PLoS One. 2014 Dec 8;9(12):e113990. doi: 10.1371/journal.pone.0113990. eCollection 2014.

本文引用的文献

1
Ultrastructural changes in the cochlear duct following mechanical disruption of the organ of Corti.
Ann Otol Rhinol Laryngol. 1969 Apr;78(2):342-57. doi: 10.1177/000348946907800213.
2
[Electron microscopical examination of diffusion and resorption of thorium dioxide in the cochlea of the guinea pig. 4. Basilar membrane and organ of Corti].[二氧化钍在豚鼠耳蜗中的扩散与吸收的电子显微镜检查。4. 基底膜与柯蒂氏器]
Arch Klin Exp Ohren Nasen Kehlkopfheilkd. 1968;192(4):384-400.
3
Permeability of the inner ear membranes.内耳膜的通透性。
Acta Otolaryngol. 1969 Feb-Mar;67(2):165-70. doi: 10.3109/00016486909125439.
4
Separation of the organ of Corti into its component cells.将柯蒂氏器分离成其组成细胞。
Ann Otol Rhinol Laryngol. 1967 Jun;76(2):414-26. doi: 10.1177/000348946707600210.
5
Hearing loss due to continuous exposure to steady-state broad-band noise.由于持续暴露于稳态宽带噪声而导致的听力损失。
J Acoust Soc Am. 1974 Nov;56(5):1585-93. doi: 10.1121/1.1903482.