[Activity of postheparin lipoprotein lipase in rabbit blood plasma].

Activity of lipoprotein lipase was studied in rabbit blood plasma after administration of heparin at a dose 50 un/kg into animals. NaCl was added to incubation mixture at final concentration 1 M to differentiate the enzyme from liver triglyceride lipase. The salt inhibited strongly (sometimes completely) the lipolytic activity in rabbit postheparin blood plasma. These data suggest predominance of lipoprotein lipase, sensitive to NaCl, in total lipolytic activity of rabbit postheparin blood plasma. Only slight alterations in the value of total lipolytic activity and in activity, depending on lipoprotein lipase, were observed in rabbits maintained at high cholesterol diet. Under these conditions distinct increase in activity of triglyceride lipase, stable to NaCl , was not found.