Hedrick P W
Genetics. 1974 Oct;78(2):757-70. doi: 10.1093/genetics/78.2.757.
The conditions for a stable polymorphism and the equilibrium gene frequency in an infinite population are compared when there is spatial or temporal environmental heterogeneity for the absolute dominance model. For temporal variation the conditions for stability are more restrictive and the equilibrium gene frequency is often at a low gene frequency. In a finite population, temporal environmental heterogeneity for the absolute dominance model was found to be quite ineffective in maintaining genetic variation and is often less effective than no selection at all. For comparison, the maximum maintenance for temporal variation is related to the overdominant model. In general, cyclic environmental variation was found to be more effective at maintaining genetic variation than where the environment varies stochastically. The importance of temporal environmental variation and the maintenance of genetic variation is discussed.
当绝对显性模型存在空间或时间环境异质性时，比较了无限种群中稳定多态性的条件和平衡基因频率。对于时间变化，稳定性条件更具限制性，平衡基因频率通常处于低基因频率。在有限种群中，发现绝对显性模型的时间环境异质性在维持遗传变异方面相当无效，而且通常比完全不进行选择更无效。为作比较，时间变化的最大维持量与超显性模型有关。一般来说，发现周期性环境变化在维持遗传变异方面比环境随机变化更有效。讨论了时间环境变化的重要性以及遗传变异的维持。
