Moult P J, Lunzer M R, Trash D B, Sherlock S
Gut. 1974 Dec;15(12):988-92. doi: 10.1136/gut.15.12.988.
Bumetanide is an effective diuretic for the treatment of ascites. Fifteen out of 17 patients with chronic liver disease responded satisfactorily and the incidence of hepatic encephalopathy and electrolyte disturbances was similar to that previously observed with frusemide. Colicky abdominal pain was reported in three patients but no other adverse effects were noted. An unexpected response was obtained in two patients who had diuresis without natriuresis.
布美他尼是治疗腹水的一种有效利尿剂。17例慢性肝病患者中有15例反应良好,肝性脑病和电解质紊乱的发生率与先前使用速尿时观察到的相似。3例患者报告有绞痛性腹痛,但未观察到其他不良反应。有2例患者出现了不排钠的利尿反应,这是一种意外的反应。