L-亮氨酸和L-苯丙氨酸诱导的胰岛素释放及D-葡萄糖的影响。大鼠胰腺灌注的动力学研究。 - Suppr

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超能文献

L-leucine and L-phenylalanine induced insulin release and the influence of D-glucose. Kinetic studies with the perfused rat pancreas.

作者信息

Landgraf R, Landgraf-Leurs M M, Hörl R

出版信息

Diabetologia. 1974 Oct;10(5):415-20. doi: 10.1007/BF01221631.

DOI:10.1007/BF01221631

PMID:4452428

Abstract

摘要

相似文献

L-leucine and L-phenylalanine induced insulin release and the influence of D-glucose. Kinetic studies with the perfused rat pancreas.L-亮氨酸和L-苯丙氨酸诱导的胰岛素释放及D-葡萄糖的影响。大鼠胰腺灌注的动力学研究。

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Stimulation of insulin secretion in vitro by essential aminoacids.必需氨基酸对体外胰岛素分泌的刺激作用。

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Insulin secretion studied in the perfused rat pancreas. I. Effect of tolbutamide, leucine and arginine; their interaction with diazoxide, and relation to glucose.在灌注大鼠胰腺中研究胰岛素分泌。I. 甲苯磺丁脲、亮氨酸和精氨酸的作用；它们与二氮嗪的相互作用以及与葡萄糖的关系。

Diabetes. 1971 Jul;20(7):449-56. doi: 10.2337/diab.20.7.449.

Effects of N-[(trans-4-isopropylcyclohexyl)-carbonyl]-D-phenylalanine (A-4166) on insulin and glucagon secretion in isolated perfused rat pancreas.N-[(反式-4-异丙基环己基)-羰基]-D-苯丙氨酸（A-4166）对离体灌注大鼠胰腺胰岛素和胰高血糖素分泌的影响。

Pharmacology. 1994 Apr;48(4):205-10. doi: 10.1159/000139181.

[Effect of glucose and of insulin on the fast induced decrease of insulin response to glucose of the in vitro perfused rat pancreas].[葡萄糖及胰岛素对体外灌注大鼠胰腺快速诱导的葡萄糖胰岛素反应降低的影响]

C R Seances Soc Biol Fil. 1975;169(3):606-10.

Amino acid--induced insulin release from the perfused rat pancreas. The influence of phenylalanine and tyrosine.

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Ay-4166 increases the sensitivity of insulin secretion to glucose in isolated perfused rat pancreas.

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L-Leucine-induced secretion of glucagon and insulin, and the "off-response" to L-leucine in vitro. I. Characterization of the dynamics of secretion.

Endocrinology. 1978 Oct;103(4):1208-18. doi: 10.1210/endo-103-4-1208.

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Ingestion of leucine + phenylalanine with glucose produces an additive effect on serum insulin but less than additive effect on plasma glucose.亮氨酸 + 苯丙氨酸与葡萄糖一起摄入时，对血清胰岛素产生相加作用，但对血糖的作用小于相加作用。

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Effect of amino-acids on secretion of insulin by isolated islets of the monkey.氨基酸对猴胰岛分离物胰岛素分泌的影响。

Diabetologia. 1982 Dec;23(6):541-3. doi: 10.1007/BF00254308.

Previous exposure to glucose enhances somatostatin secretion from the isolated perfused rat pancreas.先前接触葡萄糖可增强离体灌注大鼠胰腺的生长抑素分泌。

Diabetologia. 1981 Apr;20(4):495-500. doi: 10.1007/BF00253414.

Plasma amino acid values and pancreatic beta-cell function in phenylketonuria.

J Inherit Metab Dis. 1987;10(1):66-72. doi: 10.1007/BF01799491.

Evidence for inhibition of exodus of small neutral amino acids from non-brain tissues in hyperphenylalaninaemic rats.高苯丙氨酸血症大鼠非脑组织中小中性氨基酸外流受抑制的证据。

J Inherit Metab Dis. 1989;12(2):166-80. doi: 10.1007/BF01800722.

Leucine and tissue distribution of bulky and small neutral amino acids in rats: dissociation between transport and insulin-mediated effects.大鼠中亮氨酸以及大分子和小分子中性氨基酸的组织分布：转运与胰岛素介导效应之间的分离

J Inherit Metab Dis. 1992;15(1):145-54. doi: 10.1007/BF01800357.

Sulphydryl requirement for insulin release from the perfused pancreas. Studies with ethacrynic acid and dithiothreitol.灌注胰腺释放胰岛素对巯基的需求。用依他尼酸和二硫苏糖醇进行的研究。

Diabetologia. 1978 Oct;15(4):337-42. doi: 10.1007/BF03160999.

本文引用的文献

EFFECT OF ISCHEMIA ON KNOWN SUBSTRATES AND COFACTORS OF THE GLYCOLYTIC PATHWAY IN BRAIN.缺血对脑糖酵解途径已知底物和辅助因子的影响。

J Biol Chem. 1964 Jan;239:18-30.

Immunoassay of insulin with insulin-antibody precipitate.用胰岛素 - 抗体沉淀物进行胰岛素免疫测定。

Biochem J. 1963 Jul;88(1):137-46. doi: 10.1042/bj0880137.

An in vitro method for studying insulin secretion in the perfused isolated rat pancreas.一种用于研究灌注离体大鼠胰腺中胰岛素分泌的体外方法。

Metabolism. 1966 May;15(5):466-76. doi: 10.1016/0026-0495(66)90089-8.

Organ culture of fetal rat pancreas. II. Insulin release induced by amino and organic acids, by hormonal peptides, by cationic alterations of the medium and by other agents.胎鼠胰腺的器官培养。II. 氨基酸、有机酸、激素肽、培养基阳离子改变及其他试剂诱导的胰岛素释放。

Biochim Biophys Acta. 1969 Sep 2;184(3):540-53. doi: 10.1016/0304-4165(69)90268-2.

Diabetes. 1971 Jul;20(7):449-56. doi: 10.2337/diab.20.7.449.

Enhancement of arginine-induced insulin secretion in man by prior administration of glucose.预先给予葡萄糖可增强精氨酸对人胰岛素分泌的诱导作用。

Diabetes. 1971 Mar;20(3):171-6. doi: 10.2337/diab.20.3.171.

Is there a common beta cell insulin compartment stimulated by glucose and tolbutamide?是否存在一个由葡萄糖和甲苯磺丁脲刺激的共同的β细胞胰岛素池？

Am J Physiol. 1971 Feb;220(2):319-23. doi: 10.1152/ajplegacy.1971.220.2.319.

Synergistic effect of certain amino acid pairs upon insulin secretion in man.

Diabetes. 1970 Feb;19(2):102-8. doi: 10.2337/diab.19.2.102.

Kinetics of insulin release from the perfused rat pancreas caused by glucose, glucosamine, and galactose.葡萄糖、氨基葡萄糖和半乳糖引起的灌注大鼠胰腺胰岛素释放动力学。

Proc Natl Acad Sci U S A. 1971 Mar;68(3):536-40. doi: 10.1073/pnas.68.3.536.

The effect of cycloheximide and 2-deoxyglucose on the diphasic pattern of insulin secretion.

Acta Diabetol Lat. 1971 Jan-Feb;8(1):48-65. doi: 10.1007/BF01550857.

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