Bondy S C, Tepper J M, Bettis D B
Neurochem Res. 1979 Dec;4(6):755-61. doi: 10.1007/BF00964472.
The ability of midbrain homogenates from two strains of mice to accumulate several putative neurotransmitters, or their precursor in the case of acetylcholine, has been examined. The high-affinity transport mechanisms toward glutamate, GABA, dopamine, and glycine were similar in both strains. The seizure-prone DBA21BG strain had a significantly higher capacity to transport choline than did the relatively seizure-resistant C57BL/6 IBC mice. Howaver, no difference in the density of muscarinic binding sites in the two mouse strains was found.
已对两种品系小鼠的中脑匀浆积累几种假定神经递质或其前体（如乙酰胆碱的前体）的能力进行了检测。两种品系对谷氨酸、γ-氨基丁酸、多巴胺和甘氨酸的高亲和力转运机制相似。易发生癫痫的DBA21BG品系比相对抗癫痫的C57BL/6 IBC小鼠具有显著更高的胆碱转运能力。然而，未发现两种小鼠品系毒蕈碱结合位点密度存在差异。
