Laniado S, Buckley N M, Frank C W, Kambosos D
Cardiology. 1974;59(4):253-67. doi: 10.1159/000169688.
Effects of DC electric countershock on cardiac function in thoracotomized dogs were evaluated from recordings of ECG, aortic pressure, left ventircular pressure and its first derivative, and coronary sinus flow. Samples of arterial and coronary venous plasma and left ventricular myocardium obtained before and after countershock at times corresponding to post-shock arrhythmias and recovery were analyzed for Mg++, K+ and Ca++, and norepinephrine. At 1 min after countershock, ECG changes included transient cardiac arrhythmias and ST segment alterations, accompanied by depressed ventricular function and decreased myocardial Ca++ concentration. At 5 min postshock, coronary venous Mg++ and K+ concentrations had risen and ventricular function was still depressed. Function recovered within 10-20 min. There was no evidence of consistent loss of endogenous myocardial norepinephrine.
通过记录心电图、主动脉压力、左心室压力及其一阶导数以及冠状窦血流，评估直流电复律对开胸犬心脏功能的影响。在与电击后心律失常和恢复相对应的时间，采集电击前后的动脉和冠状静脉血浆样本以及左心室心肌样本，分析其中的镁离子、钾离子、钙离子和去甲肾上腺素。电击后1分钟，心电图变化包括短暂的心律失常和ST段改变，同时伴有心室功能抑制和心肌钙离子浓度降低。电击后5分钟，冠状静脉镁离子和钾离子浓度升高，心室功能仍受抑制。功能在10 - 20分钟内恢复。没有证据表明内源性心肌去甲肾上腺素持续丢失。
