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化疗与伤口愈合。

Chemotherapy and wound healing.

作者信息

Elias E G

出版信息

Clin Plast Surg. 1979 Jan;6(1):27-30.

PMID:445972
Abstract

Only patients with carcinoma of the breast who have a good prognosis after curative surgery are the best candidates for reconstructive surgery. On the other hand, patients who have a poor prognosis should not be considered for reconstructive breast surgery. Patients with guarded and intermediate prognoses who are candidates for adjuvant chemotherapy programs may be considered for reconstruction after completion of their programs and not prior to or during the programs. They should be evaluated at the end of such program, which ranges from one to two years, to assure absence of occult metastases and to assure complete bone marrow recovery. Even then, if metastases develop at a later date (after insertion of the prosthesis), tissue sloughing may occur at the site of the implant that may delay therapy or cause overwhelming infection.

摘要

只有那些在根治性手术后预后良好的乳腺癌患者才是乳房重建手术的最佳候选人。另一方面,预后较差的患者不应考虑进行乳房重建手术。对于有辅助化疗计划的预后不确定和中等预后的患者,可在其化疗计划完成后而非计划之前或期间考虑进行重建。应在这类为期一到两年的计划结束时对他们进行评估,以确保没有隐匿性转移,并确保骨髓完全恢复。即便如此,如果在后期(假体植入后)发生转移,植入部位可能会出现组织脱落,这可能会延迟治疗或导致严重感染。

相似文献

1
Chemotherapy and wound healing.化疗与伤口愈合。
Clin Plast Surg. 1979 Jan;6(1):27-30.
2
Effects of radiation therapy on wound healing after mastectomy.放射治疗对乳房切除术后伤口愈合的影响。
Clin Plast Surg. 1979 Jan;6(1):19-26.
3
Delay of adjuvant chemotherapy initiation following breast cancer surgery among elderly women.老年女性乳腺癌手术后辅助化疗起始时间的延迟
Breast Cancer Res Treat. 2006 Oct;99(3):313-21. doi: 10.1007/s10549-006-9206-z. Epub 2006 Apr 1.
4
Immediate breast reconstruction after mastectomy increases wound complications: however, initiation of adjuvant chemotherapy is not delayed.乳房切除术后立即进行乳房重建会增加伤口并发症:然而,辅助化疗的开始并未延迟。
Arch Surg. 2004 Sep;139(9):988-91. doi: 10.1001/archsurg.139.9.988.
5
Breast reconstruction following mastectomy for malignant disease: a surgical oncologist's point of view.恶性疾病乳房切除术后的乳房重建:一位外科肿瘤学家的观点。
Clin Plast Surg. 1979 Jan;6(1):5-10.
6
[Reconstructive breast surgery following mastectomy. Indication and choice of procedure].[乳房切除术后乳房重建手术。手术指征及术式选择]
MMW Munch Med Wochenschr. 1980 Aug 8;122(32-33):1131-2.
7
Prognostic significance of occult axillary lymph node metastases after chemotherapy-induced pathologic complete response of cytologically proven axillary lymph node metastases from breast cancer.乳腺癌细胞学确诊腋窝淋巴结转移化疗后病理完全缓解后隐匿性腋窝淋巴结转移的预后意义
Cancer. 2009 Apr 15;115(8):1605-12. doi: 10.1002/cncr.24173.
8
Immediate breast reconstruction does not lead to a delay in the delivery of adjuvant chemotherapy.即刻乳房重建不会导致辅助化疗的延迟。
Eur J Surg Oncol. 2004 Aug;30(6):624-7. doi: 10.1016/j.ejso.2004.04.006.
9
Implications of adjuvant hormonal and cytotoxic chemotherapy.辅助激素和细胞毒性化疗的意义。
Acta Chir Belg. 1980 Mar-Apr;79(2):89-93.
10
Prognostic value of lymph node metastases after neoadjuvant chemotherapy for large-sized operable carcinoma of the breast.新辅助化疗后大尺寸可手术乳腺癌淋巴结转移的预后价值
J Am Coll Surg. 1995 Sep;181(3):202-8.

引用本文的文献

1
Reconstruction of the breast after mastectomy for carcinoma.乳腺癌乳房切除术后的乳房重建。
Aesthetic Plast Surg. 1981;5(1):33-41. doi: 10.1007/BF01981680.
2
Reconstruction of the breast after mastectomy.乳房切除术后的乳房重建。
J R Soc Med. 1981 May;74(5):327-30. doi: 10.1177/014107688107400501.