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[膨体聚四氟乙烯血管假体——动静脉置换的新途径]

[Expanded PTFE (polytetrafluoroethylene) vascular prostheses--a new path of arterial and venous replacement].

作者信息

Hamann H, Vollmar J

出版信息

Chirurg. 1979 Apr;50(4):249-56.

PMID:446236
Abstract

Based on existing experimental and clinical observations the expanded PTFE graft shows convincing advantages in some indication fields (e.g., vascular access for hemodialysis, venous reconstruction) compared with conventional porous prostheses and biografts. On the other hand, we have to realize that expanded PTFE is not yet qualified to be the optimal substitute for small arteries. In spite of encouraging preliminary results, the use of this new type of vascular prosthesis still requires critical evaluation to avoid unpredictable failure due to uncritical surgical optimism (caution: Sparks disaster!). Further improvements may be expected from a better anchorage in the surrounding tissue (e.g., external velour), and from an increase of antithrombogenity of the inner surface.

摘要

基于现有的实验和临床观察,与传统的多孔假体和生物移植物相比,膨体聚四氟乙烯移植物在某些适应证领域(如血液透析的血管通路、静脉重建)显示出令人信服的优势。另一方面,我们必须认识到,膨体聚四氟乙烯尚未具备成为小动脉最佳替代物的条件。尽管初步结果令人鼓舞,但使用这种新型血管假体仍需要严格评估,以避免因不谨慎的手术乐观态度导致不可预测的失败(注意:火花引发灾难!)。通过在周围组织中更好地固定(如外部绒面)以及增加内表面的抗血栓形成性,有望实现进一步的改进。

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