Toyoshima H, Sugiyama S, Wada M, Sugenoya J, Toyama J
Jpn Heart J. 1974 Nov;15(6):560-78. doi: 10.1536/ihj.15.560.
Isopotential map was obtained every 3 msec after the onset of ventricular activation from 85 unipolar lead ECGs of a normal subject (Measured map) and similar map at the corresponding instant (Simulated map) was also obtained by means of mathematical calculation under the assumption that the cardiac electromotive force can be represented by a single electric dipole fixed at the heart center. These 2 maps were quantitatively compared and difference was delineated on a map (Difference map). Although, in major aspect, there was a fairly good agreement between Measured and Simulated maps during early stages of ventricular activation, a remarkable difference of potential distribution began to appear between them around the time of occurrence of epicardial breakthrough of the ventricular activation front. From that t me on, it became impossible to represent the cardiac electromotive force into 2 or more electric dipoles in Difference map. Difference maps around the instant of epicardial breakthrough of the ventricular activation were supposed to be helpful for the estimation of the spread of ventricular activation.
在一名正常受试者的85个单极导联心电图上，从心室激动开始后每隔3毫秒获取一次等电位图（实测图），并且在假设心脏电动势可用固定于心中心的单个电偶极表示的情况下，通过数学计算在相应时刻获得类似的图（模拟图）。对这两张图进行定量比较，并在一张图上描绘出差异（差异图）。虽然在心室激动早期，实测图和模拟图在主要方面有相当好的一致性，但在心室激动前沿的心外膜突破时刻左右，它们之间开始出现明显的电位分布差异。从那时起，在差异图中就无法将心脏电动势表示为两个或更多的电偶极。心室激动心外膜突破时刻左右的差异图被认为有助于估计心室激动的传播。
