Fujii J, Yazaki Y, Seki A, Kuramochi M, Muraki H
Jpn Heart J. 1974 Nov;15(6):615-22. doi: 10.1536/ihj.15.615.
Constriction of one renal artery in the presence of the opposite kidney can produce persistent hypertension which is often associated with increase in plasma renin activity, decrease in serum potassium and increase in water intake. In the present study the clipped kidney was removed in 15 hypertensive rabbits 12 to 54 weeks after the constriction. Blood pressure showed a prompt and transient fall which was followed by a slight rebound and subsequently a gradual decline. However, it still remained above the normal 5 weeks after removal. Removal of the clipped kidney resulted in return to normal of increased plasma renin activity, decreased serum potassium and increased water intake at the end of the postoperative first week.
一侧肾动脉缩窄且对侧肾脏存在时可产生持续性高血压，常伴有血浆肾素活性升高、血清钾降低及水摄入量增加。在本研究中，对15只高血压兔在肾动脉缩窄后12至54周切除夹闭侧肾脏。血压迅速且短暂下降，随后有轻微反弹，继而逐渐下降。然而，切除后5周血压仍高于正常水平。切除夹闭侧肾脏导致术后第一周结束时升高的血浆肾素活性、降低的血清钾及增加的水摄入量恢复正常。
