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血清素在未成熟大鼠诱导排卵中的作用。

The involvement of serotonin in induced ovulation in the immature rat.

作者信息

Parker V D, Soliman K F, Walker C A

出版信息

Experientia. 1979 May 15;35(5):692-4. doi: 10.1007/BF01960403.

DOI:10.1007/BF01960403
PMID:446684
Abstract

In pregnant mare's serum gonadotropin (PMS) treated immature rats the cortex, cerebellum, caudate nucleus and hypothalamus were isolated and analyzed for their serotonin (5-HT) content at 6-h intervals for 72 h. Results showed a general trend of significant variation occurring in days 1 and 3 after PMS injection with no major variations observed on the second day. The results obtained suggest a possible involvement of 5-HT in the control of ovulation.

摘要

在接受孕马血清促性腺激素(PMS)处理的未成熟大鼠中,分离出其皮质、小脑、尾状核和下丘脑,并每隔6小时分析一次它们的血清素(5-HT)含量,持续72小时。结果显示,在注射PMS后的第1天和第3天出现了显著变化的总体趋势,而在第2天未观察到主要变化。所得结果表明血清素可能参与排卵的控制。

相似文献

1
The involvement of serotonin in induced ovulation in the immature rat.血清素在未成熟大鼠诱导排卵中的作用。
Experientia. 1979 May 15;35(5):692-4. doi: 10.1007/BF01960403.
2
Brain dopamine variations in gonadotropin-treated immature rat.促性腺激素处理的未成熟大鼠脑内多巴胺的变化
Experientia. 1983 Feb 15;39(2):215-7. doi: 10.1007/BF01958909.
3
The role of hypothalamic serotonin (5HT) before ovulation in immature rats treated with pregnant mare serum (PMS).孕马血清(PMS)处理的未成熟大鼠排卵前下丘脑血清素(5-羟色胺,5HT)的作用。
Psychoneuroendocrinology. 1977;2(3):267-74. doi: 10.1016/0306-4530(77)90043-9.
4
The effect of testosterone and other adrenal steroids on PMS-induced ovulation in the immature rat.
Neuroendocrinology. 1975;17(1):27-39. doi: 10.1159/000122338.
5
Rhythms of progesterone and corticosterone in the pms-treated rat: relationship to ovulation.经经前综合征治疗的大鼠体内孕酮和皮质酮的节律:与排卵的关系。
Neuroendocrinology. 1975;17(4):319-29. doi: 10.1159/000122370.
6
Ovulation in PMS-treated rats with gonadotropin releasing hormone after pentobarbital and melatonin block.戊巴比妥和褪黑素阻断后,用促性腺激素释放激素处理的经前综合征大鼠的排卵情况。
Neuroendocrinology. 1975;19(2):170-6. doi: 10.1159/000122437.
7
Actions of pregnant mare serum gonadotropin in the immature female rat: correlative changes in blood steroids, gonadotropins, and cytoplasmic estradiol receptors of the anterior pituitary and hypothalamus.孕马血清促性腺激素对未成熟雌性大鼠的作用:血液类固醇、促性腺激素以及垂体前叶和下丘脑细胞质雌二醇受体的相关变化
Endocrinology. 1976 Jan;98(1):129-38. doi: 10.1210/endo-98-1-129.
8
Evidence for an inhibitory dopaminergic and stimulatory noradrenergic hypothalamic influence on PMS-induced ovulation in the immature rat. II. A pharmacological analysis.下丘脑多巴胺能抑制及去甲肾上腺素能刺激对未成熟大鼠经前期综合征诱导排卵影响的证据。II. 药理学分析。
Neuroendocrinology. 1977;24(5-6):289-316. doi: 10.1159/000122717.
9
Interference with the preovulatory luteinizing hormone surge and blockade of ovulation in immature pregnant mare's serum gonadotropin-primed rats with the anti-androgenic drug, hydroxyflutamide.
Biol Reprod. 1987 Apr;36(3):636-42. doi: 10.1095/biolreprod36.3.636.
10
Plasma progesterone levels in the pregnant mare's serum (PMS)-treated immature female rat.孕马血清(PMS)处理的未成熟雌性大鼠的血浆孕酮水平。
Fertil Steril. 1971 Dec;22(12):790-3.

本文引用的文献

1
The effect of 5-hydroxytryptamine and two of its antagonists on ovulation in the mouse.5-羟色胺及其两种拮抗剂对小鼠排卵的影响。
J Endocrinol. 1967 Mar;37(3):327-33. doi: 10.1677/joe.0.0370327.
2
Suppression of ovarian activity in immature rats by serotonin.
Endocrinology. 1965 Nov;77(5):937-9. doi: 10.1210/endo-77-5-937.
3
Solvent extraction method for simultaneous determination of norepinephrine, dopamine, serotonin, and 5-hydroxyindoleacetic acid in a single mouse brain.用于同时测定单只小鼠脑中去甲肾上腺素、多巴胺、5-羟色胺和5-羟基吲哚乙酸的溶剂萃取法
Anal Biochem. 1969 Aug;30(2):161-79. doi: 10.1016/0003-2697(69)90387-x.
4
Effects of selective experimental changes in regional hypothalamic monoamine levels on superovulation in the immature rat.下丘脑局部单胺水平的选择性实验性改变对未成熟大鼠超排卵的影响。
Neuroendocrinology. 1969;4(3):129-38. doi: 10.1159/000121746.
5
Blockade of superovulation in the immature rat by increased brain serotonin.脑内5-羟色胺增加对未成熟大鼠超排卵的抑制作用
Eur J Pharmacol. 1968 Sep;4(2):169-74. doi: 10.1016/0014-2999(68)90173-8.
6
Effects of serotonin on spontaneous ovulation: a theory for the dual hypothalamic control of ovulation.血清素对自发排卵的影响:一种关于排卵的双下丘脑控制理论。
Acta Endocrinol (Copenh). 1971 Oct;68(2):334-44. doi: 10.1530/acta.0.0680334.
7
A method for studying norepinephrine and serotonin metabolism in small regions of rat brain: effect of ovariectomy on amine metabolism in anterior and posterior hypothalamus.一种研究大鼠脑小区域中去甲肾上腺素和5-羟色胺代谢的方法:卵巢切除术对下丘脑前部和后部胺代谢的影响。
Endocrinology. 1971 Dec;89(6):1345-9. doi: 10.1210/endo-89-6-1345.
8
The acute effects of oestrogen and progesterone on the monoamine levels of the brain of ovariectomised rats.雌激素和孕酮对去卵巢大鼠大脑单胺水平的急性影响。
Psychopharmacologia. 1971;21(4):374-81. doi: 10.1007/BF02419060.
9
Effects of melatonin and serotonin on the release of FSH and prolactin.褪黑素和血清素对促卵泡激素及催乳素释放的影响。
Endocrinology. 1971 Jun;88(6):1288-93. doi: 10.1210/endo-88-6-1288.
10
Inhibitory effect of serotonin on ovulation in adult rats.血清素对成年大鼠排卵的抑制作用。
J Endocrinol. 1974 Feb;60(2):253-60. doi: 10.1677/joe.0.0600253.