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[双胍类制剂对脂质代谢的影响]

[The effect of biguanide preparations on lipid metabolism].

作者信息

Pavlov K

出版信息

Vutr Boles. 1974;13(6):115-8.

PMID:4467468
Abstract

The effect of biguanide preparations Silubin retard and Dibotin on cholesterin serum level and total fats was experimentally and clinically checked. The experimental investigations were carried out on rabbits with and without corticosteroid diabetes and the clinical--on 142 patients with diabetes. The bigguanide preparations was concluded to reduce both total fats and cholesterin. The higher the initial values of the mentioned indices, the more manifested their effect.

摘要

对双胍制剂水飞蓟宾延缓剂和地波亭对血清胆固醇水平及总脂肪的影响进行了实验和临床检验。实验研究在患有和未患皮质类固醇糖尿病的兔子身上进行,临床研究则在142名糖尿病患者身上开展。得出结论:双胍制剂可降低总脂肪和胆固醇。上述指标的初始值越高,其效果越明显。

相似文献

1
[The effect of biguanide preparations on lipid metabolism].[双胍类制剂对脂质代谢的影响]
Vutr Boles. 1974;13(6):115-8.
2
[The effect of butyl biguanide therapy on the serum lipid level in diabetics].
Orv Hetil. 1971 Jan 24;112(4):193-4.
3
[Treatment of diabetes mellitus with long-acting biguanides].
Probl Endokrinol (Mosk). 1976 May-Jun;22(3):22-6.
4
Changes of fibrinolytic activity in obese diabetics after treatment with Silubin retard.水飞蓟宾缓释片治疗后肥胖糖尿病患者纤溶活性的变化
Rev Roum Med Intern. 1973;10(1):23-7.
5
[Follow-up of a group of diabetics during a long-term administration of the depot form of the preparation n-butyl-biguanide (Solubin-retard Grünenthal)].[一组糖尿病患者在长期服用制剂正丁基双胍(格伦泰长效溶糖灵)的长效剂型期间的随访]
Lijec Vjesn. 1971;93(11):1233-41.
6
[Results of diabetes therapy with Silubin retard].[水飞蓟宾缓释片治疗糖尿病的结果]
Med Klin. 1966 Apr 15;61(15):592-6.
7
[Experience with the preparation n-butyl-biguanide ("Silubin")].[正丁基双胍(“西鲁宾”)的制备经验]
Med Welt. 1967 Jul 22;29:1692-3.
8
[Biguanide derivative monotherapy in diabetes].
Pol Tyg Lek. 1973 May 1;28(19):694-6.
9
[Silubin retard--long-term effects].[水飞蓟宾缓释片——长期效果]
Cas Lek Cesk. 1971 Jun 18;110(25):591-4.
10
Biguanides. A review of history, pharmacodynamics and therapy.双胍类药物。历史、药效学及治疗学综述。
Diabete Metab. 1983 May-Jun;9(2):148-63.