Libman L J, Arrowsmith D E, Dormandy T L, Heal J, Hoffbrand B I
Postgrad Med J. 1974 Nov;50(589):671-4. doi: 10.1136/pgmj.50.589.671.
The blood lipids of eight patients with previously untreated essential hypertension have been studied before and after treatment with methyldopa and bendrofluazide. No significant change was found in any of the measurements over a mean treatment period of 5·25 months. These results are believed to provide evidence that hypotensive therapy does not predispose to the development of ischaemic heart disease.
对八名未经治疗的原发性高血压患者在使用甲基多巴和苄氟噻嗪治疗前后的血脂情况进行了研究。在平均5.25个月的治疗期内,各项测量指标均未发现显著变化。这些结果被认为提供了证据,表明降压治疗不会增加缺血性心脏病的发病风险。