Matsuda R, Yamamiya T, Tatsuzawa M, Ejima A, Takai N
J Chromatogr. 1979 May 11;173(1):75-87. doi: 10.1016/s0021-9673(01)80447-7.
The separation of cold drugs and neuroleptics by high-performance liquid chromatogarphy with the porous polymer resin DVB-MCL-O (or 11-30-0), which is a styrene-divinylbenzene-methyl methacrylate copolymer substituted with hydroxymethyl groups, was studied. This copolymer was compared with the commercial porous polymers Hitachi gel 3011, 3011-0 and 3030. A very small theoretical plate height was obtained by using DVB-MCL-O and methanol-ammonia solution (99:1) as the stationary and mobile phases, respectively. This combination was found to be the most suitable for the rapid separation of condensed aromatic ring compounds.
研究了采用多孔聚合物树脂DVB-MCL-O（或11-30-0，一种用羟甲基取代的苯乙烯-二乙烯基苯-甲基丙烯酸甲酯共聚物）通过高效液相色谱法分离感冒药和抗精神病药的方法。将该共聚物与市售多孔聚合物日立凝胶3011、3011-0和3030进行了比较。分别以DVB-MCL-O和甲醇-氨溶液（99:1）作为固定相和流动相时，获得了非常小的理论塔板高度。发现这种组合最适合于快速分离稠合芳香环化合物。
