Dor X, Corone P
Herz. 1979 Apr;4(2):91-6.
An experimental study on the heart of the chick embryo demonstrates that the atrio-ventricular canal does not migrate towards the right, but that it is the inter-ampullar ring which almost completely migrates to the left. Consequently: 1. absence of migration of the interampullar ring will be responsible for the development of type A univentricular heart with an accessory chamber; 2. incomplete migration will result in a special type in which the right atrioventricular orifice overrides the septum; 3. excessive migration may be the explanation for the development of type B univentricular heart; 4. lacking or incomplete development of the inter-ampullar ring is the cause for the development of type C or D univentricular heart. In most of the cases, the univentricular heat can be considered the result of arrest of the normal embryogenesis at a more or less early state.
一项对鸡胚心脏的实验研究表明，房室管并不向右迁移，而是壶腹间环几乎完全向左迁移。因此：1. 壶腹间环不迁移将导致A型单心室心脏伴副腔的发育；2. 不完全迁移将导致一种特殊类型，其中右房室口骑跨于间隔之上；3. 过度迁移可能是B型单心室心脏发育的原因；4. 壶腹间环缺乏或发育不完全是C型或D型单心室心脏发育的原因。在大多数情况下，单心室心脏可被认为是正常胚胎发育在或多或少早期阶段停滞的结果。
