A sensitive method to measure physical and chemical carcinogen-induced "unscheduled DNA synthesis" in rapidly dividing eukaryotic cells.

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作者信息

Trosko J E, Yager J D

出版信息

Exp Cell Res. 1974 Sep;88(1):47-55. doi: 10.1016/0014-4827(74)90616-8.

DOI:10.1016/0014-4827(74)90616-8

PMID:4472970

Abstract

摘要

相似文献

A sensitive method to measure physical and chemical carcinogen-induced "unscheduled DNA synthesis" in rapidly dividing eukaryotic cells.

Exp Cell Res. 1974 Sep;88(1):47-55. doi: 10.1016/0014-4827(74)90616-8.

Intranuclear distribution of DNA repair synthesis induced by chemical carcinogens or ultraviolet light in human diploid fibroblasts.化学致癌物或紫外线诱导的人类二倍体成纤维细胞中DNA修复合成的核内分布。

Cancer Res. 1974 Dec;34(12):3461-8.

Induction of unscheduled DNA synthesis by half-nucleus irradiation of HeLa cells with an UV-microbeam in combination with hydroxyurea treatment.用紫外线微束对半核照射HeLa细胞并结合羟基脲处理诱导非预定DNA合成。

Mie Med J. 1970 Sep;20(2):93-104.

Effects of ultraviolet micro-irradiation on different parts of the cell. II. Cytological observations and unscheduled DNA synthesis after partial nuclear irradiation.紫外线微辐照对细胞不同部位的影响。II. 部分细胞核辐照后的细胞学观察和DNA的非预定合成

Exp Cell Res. 1971 Mar;65(1):129-39. doi: 10.1016/s0014-4827(71)80058-7.

[Localized incorporation of thymidine after ultraviolet micro-irradiation of the nucleus].

C R Acad Hebd Seances Acad Sci D. 1970 Feb 16;270(7):988-9.

Photosensitizing effect of trisoralen on DNA synthesis in human cells grown in vitro.

Int J Radiat Biol Relat Stud Phys Chem Med. 1971;19(1):87-92. doi: 10.1080/09553007114550101.

Responses of synchronous populations of HeLa cells to ultraviolet irradiation at selected stages of the generation cycle.处于细胞增殖周期特定阶段的同步化海拉细胞群体对紫外线照射的反应。

Radiat Res. 1967 Oct;32(2):327-46.

Prolonged ultraviolet-induced thymidine incorporation into xeroderma pigmentosum lymphocytes: studies on its duration, amount, localization and relationship to hydroxyurea.紫外线诱导的胸苷长时间掺入着色性干皮病淋巴细胞：关于其持续时间、量、定位以及与羟基脲关系的研究

Biochim Biophys Acta. 1972 Aug 16;277(1):7-14. doi: 10.1016/0005-2787(72)90345-0.

DNA repair in late-passage human cells.

Mech Ageing Dev. 1976 Jan-Feb;5(1):67-77. doi: 10.1016/0047-6374(76)90009-9.

Unscheduled DNA synthesis in hen erythrocyte nuclei reactivated in heterokaryons.在异核体中重新激活的母鸡红细胞核中的非预定DNA合成。

Exp Cell Res. 1972 Sep;74(1):131-9. doi: 10.1016/0014-4827(72)90488-0.

引用本文的文献

Kinetics of DNA Repair in Ultraviolet-Irradiated and N-acetoxy-2-acetylaminofluorene-Treated Mammalian Cells.紫外线照射和 N-乙酰氧基-2-乙酰氨基芴处理的哺乳动物细胞中 DNA 修复的动力学。

Biophys J. 1978 Dec;24(3):665-75. doi: 10.1016/S0006-3495(78)85412-5.

Alkylating agents and immunotoxins exert synergistic cytotoxic activity against ovarian cancer cells. Mechanism of action.烷化剂和免疫毒素对卵巢癌细胞具有协同细胞毒性活性。作用机制。

J Clin Invest. 1993 Nov;92(5):2440-7. doi: 10.1172/JCI116851.

Inhibitors of repair DNA synthesis.DNA修复合成抑制剂。

Nucleic Acids Res. 1982 Feb 25;10(4):1203-13. doi: 10.1093/nar/10.4.1203.

Use of scintillometric quantitation of unscheduled DNA synthesis in isolated rat hepatocytes for the screening of genotoxic agents.利用闪烁测量法对分离的大鼠肝细胞中DNA的非预定合成进行定量，以筛选遗传毒性剂。

Cell Biol Toxicol. 1987 Jun;3(2):127-42. doi: 10.1007/BF00058452.

Epidermal growth factor and proliferation in rat hepatocytes in primary culture isolated at different times after partial hepatectomy.部分肝切除术后不同时间分离的原代培养大鼠肝细胞中的表皮生长因子与增殖

Cancer Res. 1986 Mar;46(3):1318-23.

The distribution of DNA repair synthesis in chromatin and its rearrangement following damage with N-acetoxy-2-acetylaminofluorene.N-乙酰氧基-2-乙酰氨基芴损伤后染色质中DNA修复合成的分布及其重排

Nucleic Acids Res. 1978 Sep;5(9):3261-73. doi: 10.1093/nar/5.9.3261.

Differences in removal of acetylaminofluorene and pyrimidine dimers from the DNA of cultured mammalian cells.培养的哺乳动物细胞DNA中乙酰氨基芴和嘧啶二聚体去除情况的差异。

Proc Natl Acad Sci U S A. 1977 Apr;74(4):1553-7. doi: 10.1073/pnas.74.4.1553.

Different rate-limiting steps in excision repair of ultraviolet- and N-acetoxy-2-acetylaminofluorene-damaged DNA in normal human fibroblasts.

Proc Natl Acad Sci U S A. 1977 Apr;74(4):1548-52. doi: 10.1073/pnas.74.4.1548.

Interaction of chemical carcinogens and drug-metabolizing enzymes in primary cultures of hepatic cells from the rat.大鼠原代肝细胞中化学致癌物与药物代谢酶的相互作用。

Am J Pathol. 1976 Dec;85(3):755-72.

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