Courtieu A L, Moinard D, Andre M
Pathol Biol (Paris). 1979 Nov;27(9):559-64.
Between 1969 and 1978 at the CHR of Nantes we isolated Streptococcus pneumoniae from 815 swabs taken from 591 patients and which provided 595 different strains. Serotyping of all the strains was carried out using the capsular reaction test. The prevalence of the different serovars varied according to the year and the type of swab. No resistant strains to benzylpenicillin or ampicillin were observed. There was significant resistance to sulphonamides and tetracycline : 24,3 and 29,6% respectively. The American vaccine containing the greatest number of serovars was effective for only 69,8% of the strains isolated in Nantes.
1969年至1978年间，在南特市儿童医院，我们从591名患者的815份拭子中分离出肺炎链球菌，共得到595种不同菌株。所有菌株均采用荚膜反应试验进行血清分型。不同血清型的流行率因年份和拭子类型而异。未观察到对苄青霉素或氨苄青霉素耐药的菌株。对磺胺类药物和四环素存在显著耐药性，分别为24.3%和29.6%。包含血清型数量最多的美国疫苗对在南特分离出的菌株仅69.8%有效。
