Balagura S, Frantz A G, Housepian E M, Carmel P W
J Neurosurg. 1979 Jul;51(1):42-6. doi: 10.3171/jns.1979.51.1.0042.
Serum prolactin levels were determined in 205 patients with a variety of intracranial diseases, including 70 cases with pituitary tumors. It is concluded that although the absence of elevated prolactin levels does not help to rule out pituitary pathology, the presence of hyperprolactinemia is highly specific for diseases of the pituitary and hypothalamus, and prolactin determination should be part of the regular work-up of pituitary tumor suspects. Excluding known causes of hyperprolactinemia, such as tranquilizing drug ingestion, the presence of neurological disease outside the hypothalamic-pituitary area was not associated with increased serum prolactin concentrations.
对205例患有各种颅内疾病的患者测定了血清催乳素水平，其中包括70例垂体肿瘤患者。得出的结论是，虽然催乳素水平未升高无助于排除垂体病变，但高催乳素血症的存在对垂体和下丘脑疾病具有高度特异性，催乳素测定应作为垂体肿瘤疑似患者常规检查的一部分。排除高催乳素血症的已知原因，如下镇静药物摄入，下丘脑-垂体区域以外的神经系统疾病与血清催乳素浓度升高无关。
