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Influence of first-pass effect on the systemic availability of propoxyphene.

作者信息

Perrier D, Gibaldi M

出版信息

J Clin Pharmacol New Drugs. 1972 Nov-Dec;12(11):449-52. doi: 10.1002/j.1552-4604.1972.tb00245.x.

DOI:10.1002/j.1552-4604.1972.tb00245.x
PMID:4484660
Abstract
摘要

相似文献

1
Influence of first-pass effect on the systemic availability of propoxyphene.
J Clin Pharmacol New Drugs. 1972 Nov-Dec;12(11):449-52. doi: 10.1002/j.1552-4604.1972.tb00245.x.
2
d-Propoxyphene kinetics after single oral and intravenous doses in man.
Clin Pharmacol Ther. 1979 Oct;26(4):473-82. doi: 10.1002/cpt1979264473.
3
Effect of l-propoxyphene on plasma levels and analgesic activity of d-propoxyphene in the rat.左旋丙氧芬对大鼠体内右旋丙氧芬血浆水平及镇痛活性的影响。
J Pharmacol Exp Ther. 1976 Nov;199(2):415-22.
4
Plasma concentrations of propoxyphene in man. II. Pharmacokinetics.人体内丙氧芬的血浆浓度。II. 药代动力学。
Int Z Klin Pharmakol Ther Toxikol. 1972 Feb;5(4):381-8.
5
The effect of ethanol intake on propoxyphene absorption and biotransformation in dogs.乙醇摄入对犬体内丙氧芬吸收及生物转化的影响。
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6
Concentration of propoxyphene in human plasma following oral, intramuscular, and intravenous administration.口服、肌肉注射和静脉注射后人体血浆中丙氧芬的浓度。
Toxicol Appl Pharmacol. 1971 Jul;19(3):480-92. doi: 10.1016/0041-008x(71)90006-8.
7
Disposition of propoxyphene and norpropoxyphene in man after a single oral dose.
Clin Pharmacol Ther. 1974 Mar;15(3):302-9. doi: 10.1002/cpt1974153302.
8
Propoxyphene and norpropoxyphene plasma concentrations in the anephric patient.
Clin Pharmacol Ther. 1980 May;27(5):665-70. doi: 10.1038/clpt.1980.94.
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Analgesia, plasma levels, and dosage of propoxyphene.丙氧芬的镇痛效果、血浆水平及剂量
Int J Clin Pharmacol Biopharm. 1976 Apr;13(3):177-81.
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Plasma concentrations of propoxyphene in man. I. Following oral administration of the drug in solution and capsule forms.人体内丙氧芬的血浆浓度。I. 口服溶液剂和胶囊剂后的情况。
Int Z Klin Pharmakol Ther Toxikol. 1972 Feb;5(4):371-80.

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Co-proxamol is effective in chronic pain.复方丙氧氨酚对慢性疼痛有效。
BMJ. 1998 Jun 27;316(7149):1980. doi: 10.1136/bmj.316.7149.1980.
2
The cognitive and psychomotor effects of opioid analgesics. I. A randomized controlled trial of single doses of dextropropoxyphene, lorazepam and placebo in healthy subjects.阿片类镇痛药的认知和精神运动效应。I. 健康受试者单次服用右丙氧芬、劳拉西泮和安慰剂的随机对照试验。
Eur J Clin Pharmacol. 1995;48(6):447-53. doi: 10.1007/BF00194333.
3
Prediction of bioavailability for drugs with a high first-pass effect using oral clearance data.
利用口服清除率数据预测具有高首过效应药物的生物利用度。
Eur J Clin Pharmacol. 1982;22(1):85-90. doi: 10.1007/BF00606430.
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First pass effect of pinazepam in the rabbit liver.匹那西泮在兔肝脏中的首过效应。
Eur J Drug Metab Pharmacokinet. 1982;7(2):119-22. doi: 10.1007/BF03188728.
5
Pharmacokinetics of the hepatobiliary transport of bromphenol blue as a model of organic anionic compounds.
J Pharmacokinet Biopharm. 1974 Dec;2(6):495-509. doi: 10.1007/BF01070944.
6
Problems associated with bioavailability and dosage regiment studies in man.与人体生物利用度和给药方案研究相关的问题。
J Pharmacokinet Biopharm. 1974 Aug;2(4):365-77. doi: 10.1007/BF01061408.
7
Dextropropoxyphene kinetics after single and repeated oral doses in man.右丙氧芬在人体单次及多次口服给药后的动力学
Eur J Clin Pharmacol. 1985;29(1):79-84. doi: 10.1007/BF00547373.
8
Pharmacokinetics of dextropropoxyphene and nordextropropoxyphene in young and elderly volunteers after single and multiple dextropropoxyphene dosage.右丙氧芬和去甲右丙氧芬在年轻和老年志愿者单次及多次服用右丙氧芬后的药代动力学
Br J Clin Pharmacol. 1989 Oct;28(4):463-9. doi: 10.1111/j.1365-2125.1989.tb03527.x.
9
Pharmacokinetics of chlormethiazole in humans.氯美噻唑在人体内的药代动力学。
Eur J Clin Pharmacol. 1975 Jun 13;8(5):353-7. doi: 10.1007/BF00562662.
10
Quantitation of hepatic and pulmonary first-pass effects and its implications in pharmacokinetic study. I. Pharmacokinetics of chloroform in man.
J Pharmacokinet Biopharm. 1975 Jun;3(3):193-201. doi: 10.1007/BF01067908.