Action of ammonium ions on the resting membrane of crayfish stretch receptor neuron.

In the crayfish stretch receptor neuron, extracellularly applied NH4+ acted on the nonsynaptic membrane and produced not only a depolarizing shift of EIPSP but also depolarization and conductance increase. Under certain conditions these actions may become the main cause of the disinhibitory effect of NH4+ on the inhibitory synapse.