Gazenko O G, Grigor'ev A I, Degtiarev V A, Kakurin L I, Kozyrevskaia G I
Kosm Biol Aviakosm Med. 1979 May-Jun;13(3):10-5.
The water-salt supplement developed in ground-based experiments in order to increase human tolerance to LBNP and orthostatic tests was recommended to be given to the crewmembers at the final stage of the second expedition of Salyut-4. On the 53rd flight day, concomitantly with an intake of 4.0 g sodium chloride and 900-1200 ml water, an LBNP test was carried out to assess the effectiveness of this supplement, to select its optimal doses and to clarify individual responses. After the intake both cosmonauts showed a better tolerance of the LBNP test. They also displayed individual variations in their responses, viz. the commander in arterial circulation, and the flightengineer in venous circulation. As suggested by the ground-based experiments and the inflight provocative test, both cosmonauts were requested to take 9.0 g sodium chloride and 1000--1200 ml water on the last flight day. The postflight examinations demonstrated that the countermeasures applied (physical exercises, LBNP) in combination with the direct action on the fluid-electrolyte metabolism gave a pronounced positive effect.
为提高人体对下体负压（LBNP）和直立试验的耐受性而在地面实验中研发的水盐补充剂，被建议在“礼炮4号”第二次飞行任务的最后阶段提供给机组人员。在飞行第53天，在摄入4.0克氯化钠和900 - 1200毫升水的同时，进行了一次下体负压试验，以评估这种补充剂的效果，选择其最佳剂量并明确个体反应。摄入后，两名宇航员对下体负压试验均表现出更好的耐受性。他们的反应也存在个体差异，即指令长在动脉循环方面，飞行工程师在静脉循环方面。根据地面实验和飞行中的激发试验建议，要求两名宇航员在飞行最后一天摄入9.0克氯化钠和1000 - 1200毫升水。飞行后的检查表明，所采取的对策（体育锻炼、下体负压试验）与对体液电解质代谢的直接作用相结合产生了显著的积极效果。
