Zhilis B G, Kotovskiĭ E F, Uspenskiĭ L S, Petukhova G N
Kosm Biol Aviakosm Med. 1979 May-Jun;13(3):49-53.
Diuresis, glomerular filtration, tubular reabsorption (endogenous creatinine clearance), renal blood and plasma flow, total resistance of renal vessels, and filtration fraction were measured in 59 patients with mechanical (strangulation) asphyxia. Asphyxia and resulting hypoxia induced a substantial increase of diuresis, glomerular filtration and a decrease of tubular reabsorption. Disorders of renal hemodynamics which involved a decrease of renal plasma and blood flow and an increase of total resistance of renal vessels contributed significantly to the mechanism of changes of the renal excretory function. As shown by vasographic and morphological examinations, the state of intrarenal hemodynamics plays the major role in changes of the renal function.
对59例机械性（绞窄性）窒息患者进行了利尿、肾小球滤过、肾小管重吸收（内生肌酐清除率）、肾血流量和血浆流量、肾血管总阻力以及滤过分数的测定。窒息及由此导致的缺氧引起利尿和肾小球滤过显著增加，肾小管重吸收减少。肾血流动力学紊乱，包括肾血浆和血流量减少以及肾血管总阻力增加，对肾排泄功能改变机制有显著影响。血管造影和形态学检查表明，肾内血流动力学状态在肾功能改变中起主要作用。
