Aris R, Keller K H
Proc Natl Acad Sci U S A. 1972 Apr;69(4):777-9. doi: 10.1073/pnas.69.4.777.
A model is presented that suggests that a natural, stable asymmetry may arise on either side of a membrane, even when the bulk conditions on either side of the membrane are the same and the two faces of the membrane are indistinguishable. Equations are derived on the assumption of Michaelis-Menten kinetics with substrate inhibition to describe the properties of such a model membrane.
本文提出了一个模型,该模型表明,即使膜两侧的整体条件相同且膜的两个面难以区分,膜的任一侧仍可能出现自然、稳定的不对称性。基于米氏动力学并考虑底物抑制作用的假设推导出了方程,以描述这种模型膜的特性。