Lloyd-Still J D, Simon S H, Wessel H U, Gibson L E
Pediatrics. 1979 Jul;64(1):50-2.
Essential fatty acid supplementation with oral safflower oil (1 gm/kg/day) to 11 cystic fibrosis patients (aged 6 months to 14 years) for one year produced no significant change in sweat chloride concentration (mEq/liter) or sweat rate (gm/min/m2), Addition of vitamin E (10 mg/kg/day) to the safflower oil had no effect on sweat chloride concentration or rate compared to placebo. No clinical improvement could be detected compared to a control group. These results do not support previous reports of the effects of fatty acid supplementation on sweat electrolyte concentrations in cystic fibrosis.
对11名囊性纤维化患者（年龄在6个月至14岁之间）口服红花油（1克/千克/天）进行必需脂肪酸补充，为期一年，结果发现汗液氯化物浓度（毫当量/升）或出汗率（克/分钟/平方米）没有显著变化。与安慰剂相比，在红花油中添加维生素E（10毫克/千克/天）对汗液氯化物浓度或出汗率没有影响。与对照组相比，未检测到临床改善。这些结果不支持先前关于脂肪酸补充对囊性纤维化患者汗液电解质浓度影响的报道。
