Stocks P
J Hyg (Lond). 1973 Jun;71(2):237-52. doi: 10.1017/s0022172400022713.
Relative rates of proportionate mortality from cancer of six sites based on total cancer deaths and the proportions expected in all towns, and from four types of cardiovascular disease based on total deaths from all causes, have been related in the 80 county boroughs of England and Wales to the sources of water supply and to the average hardness of water in the towns. The sources of water, from upland surfaces, artesian wells and rivers, were classified in eight groups, and significant associations were found for cancers of the stomach, oesophagus, prostate, male bladder and female breast, and for hypertensive and chronic rheumatic heart disease. No associations were apparent with intestinal cancer, vascular disease of the nervous system or arteriosclerotic heart disease. Hardness or softness of the water was classified in seven groups and significant associations were found for the same diseases as for source of water, none being evident for coronary disease.
基于所有癌症死亡病例以及各城镇预期比例得出的六个部位癌症的相对比例死亡率,以及基于所有病因导致的总死亡人数得出的四种心血管疾病的相对比例死亡率,在英格兰和威尔士的80个郡级行政区中,已与供水水源及城镇水的平均硬度相关联。水源来自高地地表水、自流井和河流,被分为八组,研究发现,胃癌、食道癌、前列腺癌、男性膀胱癌和女性乳腺癌以及高血压和慢性风湿性心脏病与水源存在显著关联。而与肠癌、神经系统血管疾病或动脉硬化性心脏病未发现明显关联。水的硬度或软度被分为七组,与水源相关的相同疾病也发现了显著关联,冠心病则未发现明显关联。