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根据哈默史密斯方案治疗急性髓细胞白血病:初步报告。

Treatment of acute myeloid leukaemia according to the Hammersmith protocol: preliminary report.

作者信息

Paolino W, Resegotti L, Rossi M, Infelise V

出版信息

Br Med J. 1973 Sep 15;3(5880):567-8. doi: 10.1136/bmj.3.5880.567.

DOI:10.1136/bmj.3.5880.567
PMID:4516626
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1586843/
Abstract

A preliminary report is given of a trial of the T.R.A.P. regimen (thioguanine, rubidomycin, cytosine arabinoside, and prednisolone) for the treatment of acute myeloid leukaemia. Out of 27 patients treated 13 (48.1%) obtained complete remission. The treatment was well tolerated and produced especially good results in elderly patients.

摘要

关于采用T.R.A.P.方案(硫鸟嘌呤、柔红霉素、阿糖胞苷和泼尼松龙)治疗急性髓细胞白血病的试验给出了一份初步报告。在接受治疗的27例患者中,有13例(48.1%)获得完全缓解。该治疗耐受性良好,在老年患者中尤其取得了良好效果。

相似文献

1
Treatment of acute myeloid leukaemia according to the Hammersmith protocol: preliminary report.根据哈默史密斯方案治疗急性髓细胞白血病:初步报告。
Br Med J. 1973 Sep 15;3(5880):567-8. doi: 10.1136/bmj.3.5880.567.
2
[Comparison of the effects of cytosine arabinoside, cytosine arabinoside and thioguanine, and cytosine arabinoside and daunorubicin in acute myeloid leukemia].
Bull Cancer. 1974 Jul-Sep;61(3):411-8.
3
Preliminary results of a trial on acute myeloid leukemia comparing the effect of cytosine arabinoside, the combination of cytosine arabinoside and thioguanine and the combination of cytosine arabinoside and daunorubicine.
Recent Results Cancer Res. 1973;43:165-8.
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Multiple-drug chemotherapy for acute leukemia The TRAMPCOL regimen: results in 86 patients.急性白血病的多药化疗:TRAMPCOL方案——86例患者的治疗结果
Cancer. 1977 Jul;40(1):20-9. doi: 10.1002/1097-0142(197707)40:1<20::aid-cncr2820400106>3.0.co;2-w.
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The treatment of acute myeliod leukaemia.急性髓系白血病的治疗
J Clin Pathol. 1974 Jan;27(1):53-4. doi: 10.1136/jcp.27.1.53.
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Treatment of acute myeloid leukemia of childhood with cytosine arabinoside, daunorubicin, prednisolone, and mercaptopurine or thioguanine.
Cancer. 1975 Nov;36(5):1547-51. doi: 10.1002/1097-0142(197511)36:5<1547::aid-cncr2820360502>3.0.co;2-t.
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Prognosis of acute leukaemia in adults.成人急性白血病的预后。
Med J Aust. 1974 Jun 29;1(26):1031-5.
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Treatment of adult acute non-lymphoblastic leukemia using intermittent combination chemotherapy with daunomycin, cytosine arabinoside, 6-mercaptopurine and prednisolone-DCMP two step therapy.
Tohoku J Exp Med. 1976;118 Suppl:217-25. doi: 10.1620/tjem.118.suppl_217.
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The effect of thioguanine on a combination of daunorubicine, cytarabine and prednisone in the treatment of acute leukaemia in adults. The Finnish Leukaemia Group.硫鸟嘌呤对柔红霉素、阿糖胞苷和泼尼松联合治疗成人急性白血病的疗效。芬兰白血病研究组。
Scand J Haematol. 1979 Aug;23(2):124-8.
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The management of blastic crisis of chronic myeloid leukaemia with thioguanine, rubidomycin, ARA C and prednisone (TRAP regimen).用硫鸟嘌呤、柔红霉素、阿糖胞苷和泼尼松治疗慢性粒细胞白血病急变期(TRAP方案)。
Panminerva Med. 1973 Sep;15(9):275-7.

引用本文的文献

1
Blood and neoplastic diseases. Acute myeloblastic leukaemia.血液与肿瘤疾病。急性髓细胞白血病。
Br Med J. 1974 Nov 9;4(5940):337-9. doi: 10.1136/bmj.4.5940.337.

本文引用的文献

1
Treatment of adult acute leukemia with arabinosylcytosine and thioguanine.用阿糖胞苷和硫鸟嘌呤治疗成人急性白血病。
Cancer. 1969 May;23(5):1019-32. doi: 10.1002/1097-0142(196905)23:5<1019::aid-cncr2820230506>3.0.co;2-n.
2
Cyclophosphamide (NSC-26271), vincristine (NSC-67574), cytosine arabinoside (NSC-63878), and prednisone (NSC-10023) (COAP) combination chemotherapy for acute leukemia in adults.环磷酰胺(NSC - 26271)、长春新碱(NSC - 67574)、阿糖胞苷(NSC - 63878)和泼尼松(NSC - 10023)(COAP)联合化疗用于成人急性白血病。
Cancer Chemother Rep. 1972 Aug;56(4):543-50.
3
Management of adult acute myelogenous leukaemia.成人急性髓细胞白血病的管理
Br Med J. 1973 Jan 20;1(5846):131-7. doi: 10.1136/bmj.1.5846.131.