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犊牛汞铅中毒所致肾衰竭(作者译)

[Renal failure caused by mercury and lead poisoning in the calf (author's transl)].

作者信息

Gruys E

出版信息

Tijdschr Diergeneeskd. 1979 May 15;104(10):417-23.

PMID:451975
Abstract

The renal lesions in three calves with mercury poisoning (phenylmercuric acetate) and two calves with lead poisoning are described. In addition of slight tubular degeneration, glomerulonephritis occurred in the animals with mercury poisoning. Moreover, uraemia, oedema and haemorrhages were present. Lesions of the brain not were found. In the animals with lead poisoning, chronic renal tubular changes and characteristic intranuclear inclusion bodies in the proximal tubular cells were observed. The juxtamedullary glomeruli showed proliferative mesangial lesions. In one calf, the cerebral cortex showed oedema, necrosis of neurons and an increase in glial cells.

摘要

描述了三头汞中毒(醋酸苯汞)犊牛和两头铅中毒犊牛的肾脏病变。除了轻微的肾小管变性外,汞中毒的动物还发生了肾小球肾炎。此外,还出现了尿毒症、水肿和出血。未发现脑部病变。在铅中毒的动物中,观察到慢性肾小管变化以及近端肾小管细胞中特征性的核内包涵体。近髓肾小球显示系膜增生性病变。在一头犊牛中,大脑皮层出现水肿、神经元坏死和神经胶质细胞增多。

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