Lane N J
Tissue Cell. 1979;11(1):1-18. doi: 10.1016/0040-8166(79)90002-8.
Non-junctional intramembranous particle arrays in the form of ridges, bracelets or rectilinear assemblies have been found by freeze-fracturing in the cytoplasmic half or P face of the plasma membrane in a variety of arthropod tissues. These tissues include both excitable cells, nerve and muscle, and such other cells as those from the intestinal tract, the tracheal system and the connective tissue. The intramembranous ridges are short rows of fused particles about 10 nm in diameter; comparable particles comprise the bracelets and the rectilinear aggregates, although the former are of lower profile. In cells sending out cytoplasmic projections during migration and development, for example, axons in embryonic, newly hatched or pupal tissues, tracheoles or fibroblasts, the intramembranous ridges are always aligned parallel to the longitudinal axis of the cellular process. The physiological significance of these may be that they play some role in recognition during development, perhaps by contact guidance. The ridges and rectilinear arrays found in the gut could also be involved in recognition and/or adhesion. In muscle, bead-like ridges are intimately associated with the transverse tubular system and may have a receptor function. Irregular and circular low-profile ridges occur in the tissues of the horseshoe crab, Limulus, and 'bracelet' forms are found in the inner membrane of insect pupal tracheae. The latter may play a part in the initiation and development of small tracheoles.
通过冷冻蚀刻技术，在多种节肢动物组织细胞膜的细胞质半层或P面中发现了呈嵴、环状或直线状排列的非连接膜内颗粒阵列。这些组织既包括可兴奋细胞，如神经和肌肉，也包括其他细胞，如来自肠道、气管系统和结缔组织的细胞。膜内嵴是由直径约10纳米的融合颗粒组成的短排；类似的颗粒构成了环状结构和直线状聚集体，尽管前者的轮廓较低。在迁移和发育过程中发出细胞质突起的细胞中，例如胚胎、新孵化或蛹期组织中的轴突、微气管或成纤维细胞，膜内嵴总是与细胞突起的纵轴平行排列。其生理意义可能是它们在发育过程中的识别中发挥某种作用，也许是通过接触导向。在肠道中发现的嵴和直线状阵列也可能参与识别和/或黏附。在肌肉中，珠状嵴与横管系统密切相关，可能具有受体功能。在鲎的组织中出现不规则和圆形的低轮廓嵴，在昆虫蛹期气管的内膜中发现“环状”结构。后者可能在微气管的起始和发育中起作用。
