Atwell R B
Vet Rec. 1979 Feb 10;104(6):114-6. doi: 10.1136/vr.104.6.114.
Four dogs with congestive heart failure associated with dirofilariasis and mitral valvular incompetence initially responded to treatment with digoxin or etamiphylline camsylate, and frusemide but became refractory to this therapy and were in cardiac decompensation. Frusemide dosage was increased and the alpha adrenoreceptor blocking drug prazosin hydrochloride was added to the therapeutic regime. Six weeks later all dogs were stabilized and their clinical condition was markedly improved.
四只患有与犬恶丝虫病和二尖瓣闭锁不全相关的充血性心力衰竭的狗，最初对洋地黄毒苷或氨茶碱 camsylate 以及速尿的治疗有反应，但对这种疗法变得难治，且处于心脏失代偿状态。速尿剂量增加，并在治疗方案中添加了α肾上腺素能受体阻断药盐酸哌唑嗪。六周后，所有狗的病情都稳定下来，临床状况明显改善。
